Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CASP3 | P42574 | 2/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12918717 | 0.87 | KDM4E (0.67) | KDM4ECYP1A2CYP2C9CYP3A4MAPT | |
| SCHEMBL9003171 | 0.85 | HPGD (0.59) | KDM4ECYP1A2CYP2C9CYP3A4MAPT | |
| SCHEMBL27701403 | 0.83 | HPGD (0.61) | KDM4ECYP1A2CYP2C9CYP3A4MAPT | |
| SCHEMBL16117354 | 0.81 | RELA (0.55) | KDM4ECYP1A2CYP2C9CYP3A4MAPT | |
| SCHEMBL14819865 | 0.79 | ESR1 (0.38) | KDM4ECYP1A2CYP2C9CYP3A4MAPT | |
| SCHEMBL14874539 | 0.77 | METAP2 (0.53) | KDM4ECYP1A2CYP2C9CYP3A4MAPT | |
| SCHEMBL14874538 | 0.77 | METAP2 (0.53) | KDM4ECYP1A2CYP2C9CYP3A4MAPT | |
| SCHEMBL13578475 | 0.71 | KDM4E (0.37) | KDM4ECYP3A4MAPTHPGDSMN1; SMN2 | |
| SCHEMBL333123 | 0.69 | CYP3A4 (0.65) | KDM4ECYP3A4ALDH1A1LMNATP53 | |
| SCHEMBL9461723 | 0.69 | CYP3A4 (0.65) | KDM4ECYP3A4ALDH1A1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2094763-B1 | POLYMERS AND FIBERS FORMED THEREFROM | DU PONT (US) | 2013-03-27 | — | — | EP | disclosed |
| US-7528217-B2 | Polymers and fibers formed therefrom | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-05-05 | — | — | US | disclosed |
| US-7528217-B2 | Polymers and fibers formed therefrom | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-05-05 | — | — | US | disclosed |
| US-20080085992-A1 | Polymers and fibers formed therefrom | DUPONT SAFETY & CONSTRUCTION, INC. | 2008-04-10 | — | — | US | disclosed |
| US-20080085992-A1 | Polymers and fibers formed therefrom | DUPONT SAFETY & CONSTRUCTION, INC. | 2008-04-10 | — | — | US | disclosed |
| US-20080014440-A1 | Polyoxadiazole composite fibers | E. I. DU PONT DE NEMOURS AND COMPANY | 2008-01-17 | — | — | US | disclosed |
| US-20080014440-A1 | Polyoxadiazole composite fibers | E. I. DU PONT DE NEMOURS AND COMPANY | 2008-01-17 | — | — | US | disclosed |