Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KLK1 | P06870 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13865263 | 0.91 | ALDH1A1 (0.37) | ALDH1A1HIF1AKLK1HRH3LMNA | |
| SCHEMBL13865264 | 0.84 | MAPT (0.41) | ALDH1A1TDP1HRH3LMNAMAPT | |
| SCHEMBL13865243 | 0.81 | ALDH1A1 (0.41) | ALDH1A1ALOX15ALOX12CYP3A4HPGD | |
| SCHEMBL8858958 | 0.75 | ALDH1A1 (0.60) | ALDH1A1ALOX15ALOX12CYP3A4HPGD | |
| SCHEMBL6336071 | 0.75 | ALDH1A1 (0.56) | ALDH1A1ALOX15ALOX12CYP3A4HPGD | |
| SCHEMBL11765295 | 0.74 | ALDH1A1 (0.51) | ALDH1A1ALOX15ALOX12CYP3A4HPGD | |
| SCHEMBL12370674 | 0.74 | ALDH1A1 (0.58) | ALDH1A1ALOX15ALOX12CYP3A4HPGD | |
| SCHEMBL25899 | 0.74 | ALDH1A1 (0.54) | ALDH1A1ALOX15ALOX12CYP3A4HPGD | |
| SCHEMBL9858715 | 0.73 | ALDH1A1 (0.47) | ALDH1A1ALOX15ALOX12CYP3A4HPGD | |
| SCHEMBL3257461 | 0.72 | THRA (0.54) | ALDH1A1ALOX15ALOX12CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7531664-B2 | Flame retarding compounds | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2009-05-12 | — | — | US | disclosed |