Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KLK1 | P06870 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 7/20 | 0.39 |
| ▸ | THRA | P10827 | 6/20 | 0.39 |
| ▸ | TLR4 | O00206 | 3/20 | 0.37 |
| ▸ | CD14 | P08571 | 3/20 | 0.37 |
| ▸ | LY96 | Q9Y6Y9 | 3/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | CD69 | Q07108 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31525571 | 0.90 | ALDH1A1 (0.47) | ALDH1A1HRH3HIF1ACYP1A2CYP2D6 | |
| SCHEMBL815088 | 0.85 | KDM4E (0.45) | ALDH1A1HRH3CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL815368 | 0.84 | MAPT (0.48) | ALDH1A1HRH3HIF1ACYP1A2CYP2D6 | |
| SCHEMBL13865263 | 0.83 | ALDH1A1 (0.37) | ALDH1A1HRH3HIF1ACYP1A2CYP2D6 | |
| SCHEMBL23014691 | 0.82 | ALDH1A1 (0.44) | ALDH1A1HRH3HIF1ACYP1A2CYP2D6 | |
| SCHEMBL4853420 | 0.80 | RXRA (0.44) | ALDH1A1HIF1ACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL6473245 | 0.79 | RXRA (0.46) | ALDH1A1HRH3HIF1ACYP1A2CYP2D6 | |
| SCHEMBL6336071 | 0.78 | ALDH1A1 (0.56) | ALDH1A1HRH3HIF1AKLK1THRB | |
| SCHEMBL8858958 | 0.78 | ALDH1A1 (0.60) | ALDH1A1HRH3HIF1AKLK1THRB | |
| SCHEMBL6472679 | 0.77 | THRA (0.46) | ALDH1A1KLK1THRBTHRATLR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0192885-B1 | HALOGENATED BISPHENOL A ETHER FLAME RETARDANT FOR ABS POLYMERS | GREAT LAKES CHEMICAL CORPORATION (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0192885-A2 | Halogenated bisphenol a ether flame retardant for ABS polymers | GREAT LAKES CHEMICAL CORPORATION (US) | 1986-09-03 | — | — | EP | disclosed |
| US-4567218-A | ACRYLONITRILE-BUTADIENE-STRYENE TERPOLYMER | GREAT LAKES CHEMICAL CORPORATION (US) | 1986-01-28 | — | — | US | disclosed |