Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 15/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2095353 | 0.84 | CYP3A4 (0.53) | KIF11MAPTKMT2AHTT | |
| SCHEMBL5329346 | 0.83 | KIF11 (0.53) | KIF11 | |
| SCHEMBL7102456 | 0.80 | MAPT (0.47) | KIF11MAPTKMT2AHTT | |
| SCHEMBL4153935 | 0.80 | CHRM3 (0.55) | MAPTKMT2AHTT | |
| SCHEMBL1529149 | 0.79 | KIF11 (0.50) | KIF11 | |
| Hydrochloric Acid SCHEMBL27310710 | 0.79 | MAPT (0.41) | KIF11MAPTKMT2AHTT | |
| SCHEMBL29730901 | 0.79 | MAPT (0.46) | KIF11MAPTKMT2AHTT | |
| SCHEMBL1492535 | 0.78 | KIF11 (0.48) | KIF11MAPTKMT2AHTT | |
| Lithium Ion SCHEMBL28436817 | 0.78 | KIF11 (0.49) | KIF11 | |
| SCHEMBL17064282 | 0.77 | MAPT (0.44) | KIF11MAPTKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111886234-B | Heterocyclic mitochondrial activity inhibitors and uses thereof | 蒙特利尔大学 | 2023-12-15 | — | — | CN | disclosed |
| US-7531573-B2 | potent, selective and safe inhibitors of the Ca2+-activated potassium channel | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2009-05-12 | — | — | US | disclosed |