SCHEMBL5329346

SCHEMBL5329346

O=C(O)CCC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 8/20 0.53
ALDH1A1 P00352 3/20 0.50
ESR1 P03372 1/20 0.50
CYP3A4 P08684 1/20 0.50
ESR2 Q92731 1/20 0.50
CYP2C19 P33261 2/20 0.47
HIF1A Q16665 2/20 0.47
KEAP1 Q14145 1/20 0.46
NR4A2 P43354 1/20 0.45
HDAC3 O15379 1/20 0.43
MAPK1 P28482 1/20 0.43
ADRA1A P35348 1/20 0.43
HDAC4 P56524 1/20 0.43
SLC6A3 Q01959 1/20 0.43
HDAC1 Q13547 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
HDAC7 Q8WUI4 1/20 0.43
HDAC2 Q92769 1/20 0.43
HDAC10 Q969S8 1/20 0.43
HDAC11 Q96DB2 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16468009 0.87 KIF11 (0.55) KIF11ALDH1A1CYP3A4CYP2C19HIF1A
SCHEMBL1633685 0.85 KIF11 (0.53) KIF11ALDH1A1CYP2C19HIF1AHDAC3
SCHEMBL23649575 0.84 KIF11 (0.43) KIF11ALDH1A1ESR1CYP3A4ESR2
Phosphine SCHEMBL29270354 0.84 KIF11 (0.52) KIF11ALDH1A1CYP2C19HIF1AHDAC3
SCHEMBL1635914 0.84 HDAC3 (0.53) KIF11ALDH1A1HDAC3MAPK1ADRA1A
SCHEMBL13865463 0.83 KIF11 (0.55) KIF11
SCHEMBL75391 0.83 ALDH1A1 (0.72) ALDH1A1ESR1CYP3A4ESR2CYP2C19
SCHEMBL1529149 0.83 KIF11 (0.50) KIF11CYP2C19HIF1ACYP1A2
Bromide SCHEMBL9938231 0.82 KIF11 (0.50) KIF11ALDH1A1CYP2C19HIF1AHDAC3
SCHEMBL4873449 0.82 CYP2C19 (0.47) KIF11ALDH1A1ESR1CYP3A4ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024059331-A1 ERYTHRITOL ESTER OF PHENYL BUTYRIC ACID AAYAM THERAPEUTICS LLC (US) 2024-03-21 WO disclosed
WO-2017205515-A1 PROCEDURE FOR THE PREPARATION OF 4-PHENYL BUTYRATE AND USES THEREOF HORIZON THERAPEUTICS, LLC (US) 2017-11-30 WO disclosed
EP-1144478-B1 VISCOSITY MODIFIER FOR THERMOSETTING RESIN COMPOSITION BLUE CUBE IP LLC (US) 2016-12-21 EP disclosed
US-7531573-B2 potent, selective and safe inhibitors of the Ca2+-activated potassium channel CHILDREN'S MEDICAL CENTER CORPORATION (US) 2009-05-12 US disclosed
US-7531573-B2 potent, selective and safe inhibitors of the Ca2+-activated potassium channel CHILDREN'S MEDICAL CENTER CORPORATION (US) 2009-05-12 US disclosed
WO-2007124459-A2 INDEX-CONTRASTING-PHOTOACTIVE POLYMERIZABLE MATERIALS, AND ARTICLES AND METHODS USING SAME INPHASE TECHNOLOGIES, INC. (US) 2007-11-01 WO disclosed
US-20070248890-A1 Index Contrasting-Photoactive Polymerizable Materials, and Articles and Methods Using Same INPHASE TECHNOLOGIES, INC. (US) 2007-10-25 US disclosed
EP-1137683-B1 POLYOXAZOLIDONE ADHESIVE RESIN COMPOSITION PREPARED FROM POLYEPOXIDES AND POLYISOCYANATES DOW GLOBAL TECHNOLOGIES INC (US) 2005-08-17 EP disclosed
US-6432541-B1 RESIN IMPREGNATED PREPREGS; METALLIC FOILS COATED WITH ADHESIVE DOW GLOBAL TECHNOLOGIES INC. 2002-08-13 US disclosed
US-6333064-B1 USEFUL FOR MAKING PREPREGS AND ELECTRICAL LAMINATES, HEAT CURABLE THE DOW CHEMICAL COMPANY 2001-12-25 US disclosed
US-4072686-A ANTIDIARRHEAL G. D. SEARLE & CO. (US) 1978-02-07 US disclosed
US-4066654-A 1-TRIARYLALKYL-4-PHENYL-4-PIPERIDINE CARBOXYLIC ACIDS AND DERIVATIVES G. D. SEARLE & CO. (US) 1978-01-03 US disclosed