Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 4/20 | 0.40 |
| ▸ | CES2 | O00748 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.32 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.32 |
| ▸ | GAPDH | P04406 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1781481 | 0.79 | CES1 (0.39) | CES1CES2TSHRALDH1A1TP53 | |
| SCHEMBL1781480 | 0.79 | CES1 (0.39) | CES1CES2TSHRALDH1A1TP53 | |
| SCHEMBL27400782 | 0.77 | CES1 (0.37) | CES1CES2TSHRALDH1A1TP53 | |
| SCHEMBL31520438 | 0.74 | CES1 (0.41) | CES1CES2TSHRALDH1A1TP53 | |
| SCHEMBL13742862 | 0.74 | — | — | |
| SCHEMBL1783776 | 0.73 | CES2 (0.41) | CES1CES2TSHRALDH1A1TRPA1 | |
| SCHEMBL1783778 | 0.73 | CES2 (0.41) | CES1CES2TSHRALDH1A1TRPA1 | |
| SCHEMBL432401 | 0.73 | AKR1B1 (0.44) | CES1CES2TSHRALDH1A1AKR1B1 | |
| SCHEMBL25131896 | 0.73 | TSHR (0.61) | TSHRTP53TRPV1FAAHMAPT | |
| SCHEMBL31130683 | 0.72 | CES1 (0.39) | CES1CES2TSHRALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8404872-B2 | Production of 2,5-dihydrofurans and analogous compounds | CORNELL UNIVERSITY (US) | 2013-03-26 | — | — | US | disclosed |
| US-20090131691-A1 | Production of 2,5-Dihydrofurans and Analogous Compounds | CORNELL RESEARCH FOUNDATION INC. (US) | 2009-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131691-A1 | Production of 2,5-Dihydrofurans and Analogous Compounds | DHPS, DHFR, DHODH | CES1 766/4885CES2 882/4885TSHR 2635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.