Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13866814 | 0.78 | CYP2C19 (0.38) | HTTHPGDALDH1A1KDM4EJAK2 | |
| SCHEMBL13866872 | 0.71 | DPP4 (0.46) | HTTHPGDALDH1A1CYP2C19CYP1A2 | |
| SCHEMBL17962160 | 0.71 | ADORA2B (0.46) | HTTHPGDALDH1A1KDM4EJAK2 | |
| SCHEMBL2496142 | 0.68 | CYP2C19 (0.61) | HTTALDH1A1CYP2C19CYP1A2RECQL | |
| SCHEMBL23620552 | 0.65 | HPGD (0.56) | HTTHPGDALDH1A1KDM4EJAK2 | |
| SCHEMBL13875830 | 0.65 | CHRNB2 (0.49) | ALDH1A1KDM4ELMNACYP2C19KMT2A | |
| SCHEMBL27887211 | 0.65 | CYP2C19 (0.58) | HTTALDH1A1CYP2C19CYP1A2RECQL | |
| SCHEMBL24401861 | 0.65 | HSD17B10 (0.43) | HTTHPGDALDH1A1KDM4EJAK2 | |
| SCHEMBL13866817 | 0.65 | LMNA (0.39) | HPGDALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL25678468 | 0.65 | KDM4E (0.46) | HTTHPGDALDH1A1KDM4EJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524847-B2 | Fused 1,3-dihydro-imidazole ring compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-04-28 | — | — | US | disclosed |