Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | CASP1 | P29466 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CASP7 | P55210 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | HTR3A | P46098 | 2/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13876140 | 0.92 | DPP4 (0.52) | DPP4HTR3AP2RX3ADORA1ADORA3 | |
| SCHEMBL13875678 | 0.90 | P2RX3 (0.40) | DPP4ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL13866887 | 0.88 | DPP4 (0.56) | DPP4ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL13866871 | 0.82 | DPP4 (0.64) | DPP4ALDH1A1HSD17B10TP53MAPK1 | |
| Trifluoroacetic Acid SCHEMBL3887064 | 0.82 | DPP4 (0.50) | DPP4ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL13875834 | 0.81 | DPP4 (0.46) | DPP4ALDH1A1CYP2C9CYP2C19HTR2C | |
| SCHEMBL13875679 | 0.81 | DPP4 (0.35) | DPP4ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL13875677 | 0.81 | P2RX3 (0.43) | DPP4ALDH1A1CYP2C9HPGDHTR2C | |
| SCHEMBL13866891 | 0.79 | DPP4 (0.60) | DPP4P2RX3 | |
| SCHEMBL13875681 | 0.78 | DPP4 (0.42) | DPP4ALDH1A1HTR2CP2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524847-B2 | Fused 1,3-dihydro-imidazole ring compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-04-28 | — | — | US | disclosed |