Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 12/20 | 0.48 |
| ▸ | MAOA | P21397 | 8/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3308921 | 0.74 | MAOB (0.83) | KMT2AMAOBMAOAMAPTACHE | |
| SCHEMBL4813362 | 0.73 | MAPT (0.67) | MAOBMAOAMAPT | |
| SCHEMBL107978 | 0.73 | MAPT (0.67) | MAOBMAOAMAPT | |
| SCHEMBL16181219 | 0.70 | MAOB (0.74) | KMT2AMAOBMAOAACHE | |
| SCHEMBL8198693 | 0.69 | RAB9A (0.55) | KMT2AMAOBMAOAACHEATM | |
| SCHEMBL178911 | 0.69 | NR3C1 (0.59) | KMT2AMAPTMEN1 | |
| SCHEMBL178909 | 0.68 | NR3C1 (0.58) | KMT2AMAPTMEN1 | |
| SCHEMBL13359889 | 0.68 | NR3C1 (0.58) | KMT2AMAPTMEN1 | |
| SCHEMBL8225508 | 0.68 | NR3C1 (0.58) | KMT2AMAPTMEN1 | |
| SCHEMBL27318392 | 0.67 | CFD (0.61) | KMT2AMAOBMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7514583-B2 | bis- and tris-dihydroxyaryl compounds and their methylenedioxy analogs; treatment of A beta , IAPP, other amyloids, and alpha -synuclein or NAC fibrillogenesis | PROTEOTECH, INC. (US) | 2009-04-07 | — | — | US | disclosed |
| US-7514583-B2 | bis- and tris-dihydroxyaryl compounds and their methylenedioxy analogs; treatment of A beta , IAPP, other amyloids, and alpha -synuclein or NAC fibrillogenesis | PROTEOTECH, INC. (US) | 2009-04-07 | — | — | US | disclosed |