SCHEMBL13868693

SCHEMBL13868693

COc1ccc(-c2cc3c4c(cc(O)c3cc2OC)C2(CC(C)(C)CCC(C)(C)C2)c2ccccc2-4)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.36
KLK7 P49862 1/20 0.36
HDAC4 P56524 2/20 0.36
HDAC2 Q92769 2/20 0.36
HDAC8 Q9BY41 2/20 0.36
ABL1 P00519 2/20 0.34
ABCB1 P08183 2/20 0.34
BCR P11274 2/20 0.34
BACE1 P56817 2/20 0.34
PDK2 Q15119 1/20 0.34
PPM1A P35813 1/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
GAA P10253 1/20 0.33
HSP90AA1 P07900 1/20 0.33
PARP1 P09874 1/20 0.32
NPC1 O15118 2/20 0.32
KDM4E B2RXH2 1/20 0.32
LMNA P02545 1/20 0.32
ALOX15 P16050 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10292865 0.95 RAB9A (0.37) RAB9AKLK7HDAC4HDAC2HDAC8
SCHEMBL13868637 0.95 RAB9A (0.37) RAB9AKLK7HDAC4HDAC2HDAC8
SCHEMBL13881220 0.94 RAB9A (0.36) RAB9AKLK7HDAC4HDAC2HDAC8
SCHEMBL13868641 0.89 HDAC4 (0.40) RAB9AKLK7HDAC4HDAC2HDAC8
SCHEMBL13868730 0.89 ERN1 (0.33) RAB9AKLK7PDK2PARP1
SCHEMBL13868732 0.89 BACE1 (0.35) RAB9AKLK7HDAC4HDAC2HDAC8
SCHEMBL10293035 0.88 PARP1 (0.35) PDK2GAAPARP1AVPR1A
SCHEMBL13868679 0.88 RAB9A (0.38) RAB9AKLK7HDAC4HDAC2HDAC8
SCHEMBL10292658 0.88 MGAM (0.38) ABL1ABCB1BCRGAAHSP90AA1
SCHEMBL10292844 0.88 AVPR1A (0.34) RAB9APDK2MEN1KMT2APARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7521004-B2 Chromene compound TOKUYAMA CORPORATION (JP) 2009-04-21 US disclosed
US-7521004-B2 Chromene compound TOKUYAMA CORPORATION (JP) 2009-04-21 US disclosed
EP-1674460-B1 CHROMENE COMPOUND TOKUYAMA CORP (JP) 2009-01-21 EP disclosed
US-20070215844-A1 Chromene Compound TOKUYAMA CORPORATION (JP) 2007-09-20 US disclosed
US-20070215844-A1 Chromene Compound TOKUYAMA CORPORATION (JP) 2007-09-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070215844-A1 Chromene Compound CRY2, TYR, CRY1 RAB9A 2789/4885KLK7 4043/4885HDAC4 2860/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.