Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.34 |
| ▸ | GPR3 | P46089 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12891216 | 0.84 | CYP3A4 (0.37) | HSD17B10TP53KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL10157173 | 0.83 | MEN1 (0.41) | HSD17B10TP53KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL12877163 | 0.76 | GPR3 (0.43) | HSD17B10TP53KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL10157237 | 0.76 | SMN1; SMN2 (0.47) | KMT2ASMN1; SMN2MEN1LMNAPDE10A | |
| SCHEMBL13038357 | 0.74 | MEN1 (0.42) | HSD17B10TP53KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL1685754 | 0.72 | TSHR (0.50) | KMT2ASMN1; SMN2LMNAKDM4EPOLB | |
| SCHEMBL10157235 | 0.71 | MEN1 (0.43) | HSD17B10TP53KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL16258491 | 0.70 | CYP3A4 (0.48) | HSD17B10TP53KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL10157230 | 0.70 | CYP3A4 (0.48) | HSD17B10TP53KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL10157239 | 0.70 | MEN1 (0.45) | HSD17B10TP53KMT2ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009062289-A1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-05-22 | — | — | WO | disclosed |