Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 7/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8939158 | 0.79 | KCNN4 (0.48) | KCNN4NPSR1CYP2C19HIF1ACYP1A2 | |
| SCHEMBL13865461 | 0.77 | KCNN4 (0.47) | KCNN4NPSR1CYP2C19HIF1ACYP1A2 | |
| SCHEMBL14342915 | 0.77 | KCNN4 (0.47) | KCNN4NPSR1CYP2C19HIF1ACYP1A2 | |
| SCHEMBL29679704 | 0.77 | KCNN4 (0.47) | KCNN4NPSR1CYP2C19HIF1ACYP1A2 | |
| SCHEMBL13828216 | 0.77 | OPRM1 (0.55) | KCNN4NPSR1CYP2C19HIF1ACYP1A2 | |
| SCHEMBL28393908 | 0.76 | CES1 (0.61) | KCNN4NPSR1CYP2C19CYP1A2CYP2C9 | |
| Hydrochloric Acid SCHEMBL1251198 | 0.76 | KCNN4 (0.45) | KCNN4NPSR1CYP2C19HIF1ACYP1A2 | |
| SCHEMBL8939171 | 0.72 | KCNN4 (0.47) | KCNN4NPSR1CYP2C19HIF1ACYP1A2 | |
| SCHEMBL30854422 | 0.72 | KCNN4 (0.52) | KCNN4NPSR1CYP2C19HIF1ACYP1A2 | |
| SCHEMBL8939167 | 0.72 | KCNN4 (0.47) | KCNN4NPSR1CYP2C19HIF1ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7531573-B2 | potent, selective and safe inhibitors of the Ca2+-activated potassium channel | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2009-05-12 | — | — | US | disclosed |