SCHEMBL29679704

SCHEMBL29679704

NCC(=O)C(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ KCNN4 O15554 7/20 0.47
▸ MAPT P10636 1/20 0.43
▸ KMT2A Q03164 1/20 0.43
▸ NPSR1 Q6W5P4 1/20 0.42
▸ CYP1A2 P05177 3/20 0.42
▸ CYP3A4 P08684 1/20 0.42
▸ RECQL P46063 1/20 0.42
▸ CYP2C19 P33261 2/20 0.42
▸ HIF1A Q16665 1/20 0.42
▸ TAAR1 Q96RJ0 1/20 0.41
▸ MAPK1 P28482 1/20 0.41
▸ KIF11 P52732 3/20 0.40
▸ CYP2C9 P11712 1/20 0.40
▸ HTT P42858 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30241803 0.84 KIF11 (0.53) KCNN4KMT2ARECQLMAPK1KIF11
SCHEMBL8939158 0.79 KCNN4 (0.48) KCNN4MAPTKMT2ANPSR1CYP1A2
SCHEMBL25848127 0.78 MAPT (0.61) KCNN4MAPTKMT2ACYP1A2CYP3A4
SCHEMBL14342915 0.77 KCNN4 (0.47) KCNN4MAPTKMT2ANPSR1CYP1A2
SCHEMBL13868873 0.77 KCNN4 (0.47) KCNN4MAPTKMT2ANPSR1CYP1A2
SCHEMBL13828216 0.77 OPRM1 (0.55) KCNN4MAPTKMT2ANPSR1CYP1A2
SCHEMBL13865461 0.77 KCNN4 (0.47) KCNN4MAPTKMT2ANPSR1CYP1A2
Hydrochloric Acid SCHEMBL29273297 0.77 MAPT (0.59) KCNN4MAPTKMT2ACYP1A2CYP3A4
SCHEMBL28393908 0.76 CES1 (0.61) KCNN4KMT2ANPSR1CYP1A2CYP3A4
Hydrochloric Acid SCHEMBL1251198 0.76 KCNN4 (0.45) KCNN4MAPTKMT2ANPSR1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250090699-A1 FAP TARGETING CYCLIC PEPTIDES AND CONJUGATES THEREOF NOVARTIS AG (CH) 2025-03-20 — — US disclosed
WO-2025037249-A1 FAP TARGETING CYCLIC PEPTIDES AND CONJUGATES THEREOF NOVARTIS AG (CH) 2025-02-20 — — WO disclosed
EP-4397673-A1 COMPOUND AND LABELED BIOMATERIAL USING SAME FUJIFILM Corporation (JP) 2024-07-10 — — EP disclosed
EP-4397671-A1 COMPOUND AND LABELED BIOMATERIAL USING SAME FUJIFILM Corporation (JP) 2024-07-10 — — EP disclosed
EP-4397672-A1 COMPOUND AND LABELED BIOMATERIAL USING SAME FUJIFILM Corporation (JP) 2024-07-10 — — EP disclosed
US-20240182383-A1 COMPOUND AND LABELED BIOLOGICAL SUBSTANCE USING THE SAME FUJIFILM CORPORATION (JP) 2024-06-06 — — US disclosed
US-20240173437-A1 COMPOUND AND LABELED BIOLOGICAL SUBSTANCE USING THE SAME FUJIFILM CORPORATION (JP) 2024-05-30 — — US disclosed
US-20240165240-A1 COMPOUND AND LABELED BIOLOGICAL SUBSTANCE USING THE SAME FUJIFILM CORPORATION (JP) 2024-05-23 — — US disclosed
CN-117642412-A Compounds and labeled biological substances using the same 富士胶片株式会社 2024-03-01 — — CN disclosed
CN-117642414-A Compounds and labeled biological substances using the same 富士胶片株式会社 2024-03-01 — — CN disclosed
CN-117642413-A Compounds and labeled biological substances using the same 富士胶片株式会社 2024-03-01 — — CN disclosed
WO-2023032996-A1 COMPOUND AND LABELED BIOMATERIAL USING SAME 富士フイルム株式会社 2023-03-09 — — WO disclosed
WO-2023032994-A1 COMPOUND AND LABELED BIOMATERIAL USING SAME 富士フイルム株式会社 2023-03-09 — — WO disclosed
WO-2023032995-A1 COMPOUND AND LABELED BIOMATERIAL USING SAME 富士フイルム株式会社 2023-03-09 — — WO disclosed
CN-108271357-B Molecular constructs for treatment of transplant rejection 免疫功坊股份有限公司 2022-06-07 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240182383-A1 COMPOUND AND LABELED BIOLOGICAL SUBSTANCE USING THE SAME SHBG, NR0B2, NR3C1 KCNN4 2256/4885MAPT 4809/4885KMT2A 3205/4885
US-20240173437-A1 COMPOUND AND LABELED BIOLOGICAL SUBSTANCE USING THE SAME OR10J3, NR2E3, NR0B2 KCNN4 2691/4885MAPT 4310/4885KMT2A 3378/4885
US-20240165240-A1 COMPOUND AND LABELED BIOLOGICAL SUBSTANCE USING THE SAME NR0B2, NR0B1, OR10J3 KCNN4 2630/4885MAPT 4444/4885KMT2A 3444/4885
US-20250090699-A1 FAP TARGETING CYCLIC PEPTIDES AND CONJUGATES THEREOF FAP, FIBP, FGF23 KCNN4 4846/4885MAPT 3257/4885KMT2A 4513/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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