Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.66 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 2/20 | 0.66 |
| ▸ | BLM | P54132 | 2/20 | 0.66 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.66 |
| ▸ | ERCC1 | P07992 | 6/20 | 0.56 |
| ▸ | ERCC4 | Q92889 | 6/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.56 |
| ▸ | APP | P05067 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | THPO | P40225 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7105545 | 0.93 | MAPT (0.74) | MAPTHSD17B10HIF1AKDM4EALDH1A1 | |
| SCHEMBL175299 | 0.89 | ERCC1 (0.66) | ERCC1ERCC4TRPV1ALPL | |
| SCHEMBL1709974 | 0.83 | MAPT (0.71) | MAPTHSD17B10HIF1AKDM4EALDH1A1 | |
| SCHEMBL30252290 | 0.83 | MAPT (0.66) | MAPTHSD17B10HIF1AKDM4EALDH1A1 | |
| SCHEMBL109163 | 0.82 | MAPT (0.74) | MAPTHSD17B10HIF1AKDM4EALDH1A1 | |
| SCHEMBL6420228 | 0.81 | MAPT (0.72) | MAPTHSD17B10HIF1AKDM4EALDH1A1 | |
| SCHEMBL107176 | 0.81 | MAPT (0.62) | MAPTHSD17B10HIF1AKDM4EALDH1A1 | |
| SCHEMBL7108607 | 0.80 | MAPT (0.73) | MAPTHSD17B10HIF1AKDM4EALDH1A1 | |
| SCHEMBL1278764 | 0.80 | MAPT (0.73) | MAPTHSD17B10HIF1AKDM4EALDH1A1 | |
| SCHEMBL10067938 | 0.80 | TRPV1 (0.68) | MAPTHSD17B10EPHX1TRPV1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8754133-B2 | Compounds, compositions and methods for the treatment of inflammatory diseases | PROTEOTECH, INC. (US) | 2014-06-17 | — | — | US | claimed |
| US-20120058998-A1 | Compounds, Compositions and Methods for the Treatment of Inflammatory Diseases | PROTAMED, INC. | 2012-03-08 | — | — | US | claimed |
| US-20070208087-A1 | Compounds, compositions and methods for the treatment of inflammatory diseases | PROTEOTECH INC. | 2007-09-06 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058998-A1 | Compounds, Compositions and Methods for the Treatment of Inflammatory Diseases | NR1H2, NR1H3, MSR1 | MAPT 1930/4885HSD17B10 368/4885HIF1A 571/4885 |
| US-20070208087-A1 | Compounds, compositions and methods for the treatment of inflammatory diseases | NR1H2, NR1H3, NR1H4 | MAPT 3290/4885HSD17B10 167/4885HIF1A 588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.