SCHEMBL1278764

SCHEMBL1278764

CCCCCCCCCCCCCCCCCCNC(=O)NCCc1ccc(O)c(O)c1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.73
TRPV1 Q8NER1 4/20 0.73
HSD17B10 Q99714 3/20 0.73
MEN1 O00255 2/20 0.73
KMT2A Q03164 2/20 0.73
HPGD P15428 3/20 0.64
KDM4E B2RXH2 2/20 0.64
LMNA P02545 2/20 0.64
BLM P54132 2/20 0.64
HIF1A Q16665 2/20 0.64
NPC1 O15118 1/20 0.64
GMNN O75496 1/20 0.64
USP2 O75604 1/20 0.64
TP53 P04637 1/20 0.64
CYP1A2 P05177 1/20 0.64
POLB P06746 1/20 0.64
CYP3A4 P08684 1/20 0.64
CYP2C9 P11712 1/20 0.64
IDE P14735 1/20 0.64
ALOX15 P16050 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7108607 1.00 MAPT (0.73) MAPTTRPV1HSD17B10MEN1KMT2A
SCHEMBL10038329 0.89 TRPV1 (0.68) MAPTTRPV1HSD17B10MEN1KMT2A
SCHEMBL10067938 0.89 TRPV1 (0.68) MAPTTRPV1HSD17B10MEN1KMT2A
SCHEMBL7105545 0.86 MAPT (0.74) MAPTTRPV1HSD17B10MEN1KMT2A
SCHEMBL7102974 0.86 MAPT (0.65) MAPTTRPV1HSD17B10MEN1KMT2A
SCHEMBL7200642 0.86 TRPV1 (0.68) MAPTTRPV1HSD17B10MEN1KMT2A
SCHEMBL3326638 0.84 TRPV1 (1.00) MAPTTRPV1HSD17B10MEN1KMT2A
SCHEMBL9345367 0.84 TRPV1 (0.80) MAPTTRPV1HSD17B10MEN1KMT2A
Hydrocaffeoylhexylamide SCHEMBL9346647 0.84 TRPV1 (0.80) MAPTTRPV1HSD17B10MEN1KMT2A
SCHEMBL3325854 0.84 TRPV1 (1.00) MAPTTRPV1HSD17B10MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2084253-B1 ULTRA-THIN WATER AND OIL REPELLENT LAYER, MANUFACTURING METHOD AND USE IN WATCHMAKING AS EPILAME ROLEX SA (CH) 2017-03-29 EP disclosed
EP-2084253-B1 ULTRA-THIN WATER AND OIL REPELLENT LAYER, MANUFACTURING METHOD AND USE IN WATCHMAKING AS EPILAME ROLEX SA (CH) 2017-03-29 EP disclosed
US-8951630-B2 Ultra-thin hydrophobic and oleophobic layer, method of manufacture and use in watchmaking as an epilame and in mechanical engineering as a barrier film ROLEX S.A. (CH) 2015-02-10 US disclosed
US-8951630-B2 Ultra-thin hydrophobic and oleophobic layer, method of manufacture and use in watchmaking as an epilame and in mechanical engineering as a barrier film ROLEX S.A. (CH) 2015-02-10 US disclosed
US-20120088099-A1 ULTRA-THIN HYDROPHOBIC AND OLEOPHOBIC LAYER, METHOD OF MANUFACTURE AND USE IN WATCHMAKING AS AN EPILAME AND IN MECHANICAL ENGINEERING AS A BARRIER FILM SUSOS AG (CH) 2012-04-12 US disclosed
US-20120088099-A1 ULTRA-THIN HYDROPHOBIC AND OLEOPHOBIC LAYER, METHOD OF MANUFACTURE AND USE IN WATCHMAKING AS AN EPILAME AND IN MECHANICAL ENGINEERING AS A BARRIER FILM SUSOS AG (CH) 2012-04-12 US disclosed
US-20100075138-A1 ULTRA-THIN HYDROPHOBIC AND OLEOPHOBIC LAYER, METHOD OF MANUFACTURE AND USE IN WATCHMAKING AS AN EPILAME ROLEX S.A. (CH) 2010-03-25 US disclosed
US-20100075138-A1 ULTRA-THIN HYDROPHOBIC AND OLEOPHOBIC LAYER, METHOD OF MANUFACTURE AND USE IN WATCHMAKING AS AN EPILAME ROLEX S.A. (CH) 2010-03-25 US disclosed
US-20100075138-A1 ULTRA-THIN HYDROPHOBIC AND OLEOPHOBIC LAYER, METHOD OF MANUFACTURE AND USE IN WATCHMAKING AS AN EPILAME ROLEX S.A. (CH) 2010-03-25 US disclosed
EP-2084253-A1 ULTRA-THIN HYDROPHOBIC AND OLEOPHOBIC LAYER, ITS METHOD OF MANUFACTURE AND USE IN CLOCKMAKING AS AN EPILAME ROLEX SA (CH) 2009-08-05 EP disclosed
WO-2008064513-A1 ULTRA-THIN HYDROPHOBIC AND OLEOPHOBIC LAYER, ITS METHOD OF MANUFACTURE AND USE IN MECHANICS AS A BARRIER FILM SUSOS AG (CH) 2008-06-05 WO disclosed
WO-2008064513-A1 ULTRA-THIN HYDROPHOBIC AND OLEOPHOBIC LAYER, ITS METHOD OF MANUFACTURE AND USE IN MECHANICS AS A BARRIER FILM SUSOS AG (CH) 2008-06-05 WO disclosed
WO-2008064511-A1 ULTRA-THIN HYDROPHOBIC AND OLEOPHOBIC LAYER, ITS METHOD OF MANUFACTURE AND USE IN CLOCKMAKING AS AN EPILAME ROLEX S.A. (CH) 2008-06-05 WO disclosed
WO-2008064511-A1 ULTRA-THIN HYDROPHOBIC AND OLEOPHOBIC LAYER, ITS METHOD OF MANUFACTURE AND USE IN CLOCKMAKING AS AN EPILAME ROLEX S.A. (CH) 2008-06-05 WO disclosed
EP-1927649-A1 Ultra-thin water and oil repellent layer, manufacturing method and use in mechanics as a barrier film SurfaceSolutions GmbH (CH) 2008-06-04 EP disclosed
EP-1927649-A1 Ultra-thin water and oil repellent layer, manufacturing method and use in mechanics as a barrier film SurfaceSolutions GmbH (CH) 2008-06-04 EP disclosed
EP-1927648-A1 Ultra-thin water and oil repellent layer, manufacturing method and use in watchmaking as epilame ROLEX SA (CH) 2008-06-04 EP disclosed
EP-1927648-A1 Ultra-thin water and oil repellent layer, manufacturing method and use in watchmaking as epilame ROLEX SA (CH) 2008-06-04 EP disclosed
US-6596669-B1 Comprising a support and two reversible heat-sensitive recording layers having different colors formed on the same side of the support, comprising colorless electron-donative dye precursor and an electron-accepting compound MITSUBISHI PAPER MILLS LIMITED (JP) 2003-07-22 US disclosed
US-6004899-A SURFACE TREATED WITH SILANE, TITANATE, AND/OR ALUMINUM COUPLING AGENT; PIGMENT; ERASIBILITY MITSUBISHI PAPER MILLS LIMITED (JP) 1999-12-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100075138-A1 ULTRA-THIN HYDROPHOBIC AND OLEOPHOBIC LAYER, METHOD OF MANUFACTURE AND USE IN WATCHMAKING AS AN EPILAME KCNH3, HCN3, HCN4 MAPT 4234/4885TRPV1 966/4885HSD17B10 2782/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.