Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.73 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.73 |
| ▸ | MEN1 | O00255 | 2/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.73 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | BLM | P54132 | 2/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | GMNN | O75496 | 1/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | IDE | P14735 | 1/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1278764 | 1.00 | MAPT (0.73) | MAPTTRPV1HSD17B10MEN1KMT2A | |
| SCHEMBL10038329 | 0.89 | TRPV1 (0.68) | MAPTTRPV1HSD17B10MEN1KMT2A | |
| SCHEMBL10067938 | 0.89 | TRPV1 (0.68) | MAPTTRPV1HSD17B10MEN1KMT2A | |
| SCHEMBL7105545 | 0.86 | MAPT (0.74) | MAPTTRPV1HSD17B10MEN1KMT2A | |
| SCHEMBL7102974 | 0.86 | MAPT (0.65) | MAPTTRPV1HSD17B10MEN1KMT2A | |
| SCHEMBL7200642 | 0.86 | TRPV1 (0.68) | MAPTTRPV1HSD17B10MEN1KMT2A | |
| SCHEMBL3326638 | 0.84 | TRPV1 (1.00) | MAPTTRPV1HSD17B10MEN1KMT2A | |
| SCHEMBL9345367 | 0.84 | TRPV1 (0.80) | MAPTTRPV1HSD17B10MEN1KMT2A | |
| Hydrocaffeoylhexylamide SCHEMBL9346647 | 0.84 | TRPV1 (0.80) | MAPTTRPV1HSD17B10MEN1KMT2A | |
| SCHEMBL3325854 | 0.84 | TRPV1 (1.00) | MAPTTRPV1HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030069307-A1 | 2-(3,4-Dihydroxyphenyl)ethyl-substituted carbonic acid derivatives and their use | HAARMANN & REIMER GMBH (DE) | 2003-04-10 | — | — | US | claimed |
| US-20030069307-A1 | 2-(3,4-Dihydroxyphenyl)ethyl-substituted carbonic acid derivatives and their use | HAARMANN & REIMER GMBH (DE) | 2003-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030069307-A1 | 2-(3,4-Dihydroxyphenyl)ethyl-substituted carbonic acid derivatives and their use | NFE2L2, AGER, ME2 | MAPT 2276/4885TRPV1 3999/4885HSD17B10 1254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.