Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 5/20 | 0.67 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.67 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PRCP | P42785 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28318807 | 0.87 | OPRM1 (0.57) | CHRM1CHRM2LMNATDP1SLC22A1 | |
| SCHEMBL845020 | 0.84 | ALDH1A1 (0.64) | CHRM1CHRM2SIGMAR1LMNATDP1 | |
| SCHEMBL9961314 | 0.80 | CHRM1 (0.53) | CHRM1CHRM2CHRM5CHRM3SIGMAR1 | |
| SCHEMBL11219532 | 0.78 | OPRM1 (0.58) | CHRM1CHRM2CHRM5CHRM3SIGMAR1 | |
| SCHEMBL10351842 | 0.77 | OPRM1 (0.53) | CHRM1CHRM2SLC22A1OPRM1 | |
| SCHEMBL10351516 | 0.77 | OPRM1 (0.53) | CHRM1CHRM2SLC22A1OPRM1 | |
| SCHEMBL837139 | 0.77 | ALDH1A1 (0.55) | CHRM1CHRM2CHRM5CHRM3LMNA | |
| SCHEMBL348542 | 0.74 | ALDH1A1 (0.49) | CHRM1CHRM2SIGMAR1LMNATDP1 | |
| SCHEMBL3972206 | 0.74 | ALDH1A1 (0.63) | CHRM1CHRM2CHRM5CHRM3SIGMAR1 | |
| SCHEMBL31436666 | 0.74 | OPRM1 (0.52) | CHRM1CHRM2LMNATDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1868982-B1 | COMPOUNDS THAT STIMULATE GLUCOSE UTILIZATION AND METHODS OF USE | UNIV ALBERTA (CA) | 2015-04-29 | — | — | EP | disclosed |
| US-7524885-B2 | Compounds that stimulate glucose utilization and methods of use | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2009-04-28 | — | — | US | disclosed |
| US-7524885-B2 | Compounds that stimulate glucose utilization and methods of use | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2009-04-28 | — | — | US | disclosed |