Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 7/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.45 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28318807 | 0.86 | OPRM1 (0.57) | OPRM1LMNASMN1; SMN2NPSR1TDP1 | |
| SCHEMBL26637711 | 0.86 | OPRM1 (0.61) | OPRM1LMNATDP1OPRD1OPRK1 | |
| SCHEMBL26637663 | 0.77 | OPRM1 (0.47) | OPRM1OPRD1OPRK1SLC6A4 | |
| SCHEMBL10351842 | 0.77 | OPRM1 (0.53) | OPRM1CHRM2CHRM1OPRD1OPRK1 | |
| SCHEMBL10351516 | 0.77 | OPRM1 (0.53) | OPRM1CHRM2CHRM1OPRD1OPRK1 | |
| SCHEMBL23485591 | 0.76 | OPRM1 (0.43) | OPRM1LMNASMN1; SMN2NPSR1TDP1 | |
| SCHEMBL26637724 | 0.75 | OPRM1 (0.55) | OPRM1OPRD1OPRK1SLC22A1SLC6A4 | |
| SCHEMBL26791021 | 0.75 | ALDH1A1 (0.46) | LMNAGAAKDM4EALDH1A1HPGD | |
| SCHEMBL11219532 | 0.75 | OPRM1 (0.58) | OPRM1ALDH1A1CHRM2CHRM1 | |
| SCHEMBL14967672 | 0.75 | ALDH1A1 (0.43) | LMNAGAAKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119486999-A | Azetidine compounds, pharmaceutical compositions thereof, methods of preparation and their use in the treatment of CNS disorders | 伊科诺姆有限公司 | 2025-02-18 | — | — | CN | claimed |
| CN-119486999-A | Azetidine compounds, pharmaceutical compositions thereof, methods of preparation and their use in the treatment of CNS disorders | 伊科诺姆有限公司 | 2025-02-18 | — | — | CN | disclosed |