Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.40 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | GAPDH | P04406 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13869284 | 0.84 | KDM4E (0.43) | KDM4ESMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL13869476 | 0.83 | KDM4E (0.37) | KDM4ESMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL13869237 | 0.83 | KDM4E (0.44) | KDM4ESMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL13869319 | 0.79 | MAOB (0.42) | KDM4EHPGDMEN1KMT2AGLA | |
| SCHEMBL13869509 | 0.78 | MAOB (0.39) | KDM4EHPGDMEN1KMT2AGLA | |
| SCHEMBL13869459 | 0.77 | PIM1 (0.41) | KDM4ESMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL13869839 | 0.75 | KDM4E (0.37) | KDM4ESMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL13869282 | 0.74 | ALDH1A1 (0.50) | KDM4ESMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL13869640 | 0.73 | MAOB (0.44) | KDM4EHPGDMEN1KMT2AGLA | |
| SCHEMBL13869828 | 0.73 | ALDH1A1 (0.42) | KDM4ESMN1; SMN2HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7514158-B2 | Coumarin compound | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2009-04-07 | — | — | US | disclosed |
| US-7514158-B2 | Coumarin compound | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2009-04-07 | — | — | US | disclosed |