Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CASR | P41180 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1386123 | 0.91 | CASR (0.41) | MEN1NPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL3942200 | 0.81 | ALOX5 (0.43) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1383385 | 0.81 | CASR (0.49) | CASRSPHK2SPHK1 | |
| SCHEMBL1385738 | 0.79 | CASR (0.46) | CASR | |
| SCHEMBL1385543 | 0.75 | CASR (0.54) | CASR | |
| SCHEMBL1384720 | 0.74 | CASR (0.46) | CASRALDH1A1 | |
| SCHEMBL1383618 | 0.74 | ALOX5 (0.47) | MEN1KMT2ASMN1; SMN2ALDH1A1MAOB | |
| SCHEMBL1383781 | 0.73 | EPHX2 (0.45) | MEN1NPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL1386105 | 0.73 | MEN1 (0.47) | MEN1NPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL1385344 | 0.73 | CASR (0.54) | CASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4825686-B2 | — | — | 2011-11-30 | — | — | JP | claimed |