Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 6/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 8/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13869185 | 0.92 | MMP3 (0.46) | MMP3HDAC1HDAC2MMP2MAPT | |
| SCHEMBL13865598 | 0.91 | LMNA (0.44) | MAPTALDH1A1LMNANPC1CYP1A2 | |
| SCHEMBL13865607 | 0.91 | LMNA (0.44) | MAPTALDH1A1LMNANPC1CYP1A2 | |
| SCHEMBL13806682 | 0.89 | MMP3 (0.42) | MMP3HDAC1HDAC2MMP2MAPT | |
| SCHEMBL13869397 | 0.88 | MAPT (0.40) | MMP3HDAC1HDAC2MMP2MAPT | |
| SCHEMBL24599323 | 0.85 | MMP3 (0.49) | MMP3HDAC1HDAC2MMP2MAPT | |
| SCHEMBL16425790 | 0.85 | MMP3 (0.49) | MMP3HDAC1HDAC2MMP2MAPT | |
| SCHEMBL14130800 | 0.85 | MMP3 (0.49) | MMP3HDAC1HDAC2MMP2MAPT | |
| SCHEMBL12676172 | 0.84 | HDAC1 (0.50) | MMP3HDAC1HDAC2MMP2MAPT | |
| SCHEMBL13865636 | 0.84 | THRB (0.40) | MMP3HDAC1HDAC2MMP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7527746-B2 | Liquid crystal polyfunctional acrylate derivative and polymer thereof | CHISSO CORPORATION (JP) | 2009-05-05 | — | — | US | disclosed |