Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | HNF4A | P41235 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.41 |
| ▸ | AHR | P35869 | 2/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13869733 | 0.87 | KDM4E (0.47) | CYP1A2KDM4EALDH1A1GAAMEN1 | |
| SCHEMBL13869256 | 0.86 | CYP1A2 (0.61) | CYP1A2KDM4EALDH1A1GAAMEN1 | |
| SCHEMBL13869701 | 0.86 | KDM4E (0.39) | CYP1A2KDM4EALDH1A1GAAMEN1 | |
| SCHEMBL13869236 | 0.84 | KDM4E (0.57) | CYP1A2KDM4EALDH1A1GAAMEN1 | |
| SCHEMBL13869307 | 0.84 | CYP1A2 (0.59) | CYP1A2KDM4EALDH1A1GAAMEN1 | |
| SCHEMBL13869287 | 0.83 | KDM4E (0.56) | CYP1A2KDM4EALDH1A1GAAMEN1 | |
| SCHEMBL13869501 | 0.82 | KDM4E (0.54) | CYP1A2KDM4EALDH1A1GAAMEN1 | |
| SCHEMBL13869534 | 0.80 | KDM4E (0.49) | CYP1A2KDM4EALDH1A1GAAMEN1 | |
| SCHEMBL13869686 | 0.79 | KDM4E (0.53) | KDM4EALDH1A1GAAMEN1MAPT | |
| SCHEMBL13869768 | 0.79 | ALDH1A1 (0.40) | CYP1A2KDM4EALDH1A1GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7514158-B2 | Coumarin compound | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2009-04-07 | — | — | US | disclosed |
| US-7514158-B2 | Coumarin compound | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2009-04-07 | — | — | US | disclosed |