Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13869733 | 0.90 | KDM4E (0.47) | ALDH1A1KDM4EMAPTHPGDMEN1 | |
| SCHEMBL13869701 | 0.82 | KDM4E (0.39) | ALDH1A1KDM4EMAPTHPGDMEN1 | |
| SCHEMBL13869749 | 0.80 | SIRT2 (0.55) | ALDH1A1KDM4EMAPTHPGDMEN1 | |
| SCHEMBL13869759 | 0.79 | CYP19A1 (0.52) | ALDH1A1KDM4EMAPTHPGDMEN1 | |
| SCHEMBL13869680 | 0.79 | CYP1A2 (0.50) | ALDH1A1KDM4EMAPTHPGDMEN1 | |
| SCHEMBL13869720 | 0.77 | ALDH1A1 (0.33) | ALDH1A1KDM4EMAPTHPGDMEN1 | |
| SCHEMBL18717942 | 0.75 | KDM4E (0.42) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL13869256 | 0.75 | CYP1A2 (0.61) | ALDH1A1KDM4EMAPTHPGDMEN1 | |
| SCHEMBL13869236 | 0.74 | KDM4E (0.57) | ALDH1A1KDM4EMAPTHPGDMEN1 | |
| SCHEMBL13869307 | 0.73 | CYP1A2 (0.59) | ALDH1A1KDM4EMAPTHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7514158-B2 | Coumarin compound | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2009-04-07 | — | — | US | disclosed |
| US-7514158-B2 | Coumarin compound | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2009-04-07 | — | — | US | disclosed |