Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.41 |
| ▸ | AHR | P35869 | 2/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.41 |
| ▸ | HNF4A | P41235 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13869768 | 0.90 | ALDH1A1 (0.40) | KDM4EALDH1A1CYP1A2GAAHPGD | |
| SCHEMBL13869680 | 0.87 | CYP1A2 (0.50) | KDM4EALDH1A1CYP1A2GAAHPGD | |
| SCHEMBL13869256 | 0.83 | CYP1A2 (0.61) | KDM4EALDH1A1CYP1A2GAAHPGD | |
| SCHEMBL13869236 | 0.81 | KDM4E (0.57) | KDM4EALDH1A1CYP1A2GAAHPGD | |
| SCHEMBL13869307 | 0.81 | CYP1A2 (0.59) | KDM4EALDH1A1CYP1A2GAAHPGD | |
| SCHEMBL13869287 | 0.80 | KDM4E (0.56) | KDM4EALDH1A1CYP1A2GAAHPGD | |
| SCHEMBL13869501 | 0.79 | KDM4E (0.54) | KDM4EALDH1A1CYP1A2GAAHPGD | |
| SCHEMBL13869749 | 0.79 | SIRT2 (0.55) | KDM4EALDH1A1GAAHPGDMAPT | |
| SCHEMBL19564381 | 0.78 | KDM4E (0.44) | KDM4EALDH1A1CYP1A2HPGDMAPT | |
| SCHEMBL23981379 | 0.77 | L3MBTL1 (0.46) | KDM4EALDH1A1CYP1A2HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7514158-B2 | Coumarin compound | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2009-04-07 | — | — | US | disclosed |
| US-7514158-B2 | Coumarin compound | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2009-04-07 | — | — | US | disclosed |