Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.47 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 8/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9843420 | 0.84 | FFAR1 (0.64) | FFAR1FFAR4AKR1B1 | |
| SCHEMBL4630671 | 0.83 | LTB4R2 (0.55) | SMN1; SMN2LTB4R2FFAR1FFAR4 | |
| SCHEMBL3993606 | 0.81 | CDK8 (0.56) | KMT2ARAB9ANPC1LTB4RLTB4R2 | |
| SCHEMBL9218201 | 0.80 | FFAR1 (0.50) | SMN1; SMN2KDM4EFFAR1FFAR4AKR1B1 | |
| SCHEMBL3998062 | 0.80 | FFAR1 (0.52) | KMT2ARAB9ANPC1SMN1; SMN2LTB4R | |
| SCHEMBL3997587 | 0.79 | FFAR1 (0.50) | SMN1; SMN2KDM4EFFAR1FFAR4AKR1B1 | |
| SCHEMBL7442885 | 0.79 | KMT2A (0.77) | KMT2AMAPK1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4630463 | 0.79 | LPAR1 (0.45) | MAPK1NPC1SMN1; SMN2FFAR1FFAR4 | |
| SCHEMBL3996108 | 0.79 | FFAR1 (0.53) | KMT2ARAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL13869734 | 0.78 | FFAR1 (0.52) | RAB9ASMN1; SMN2KDM4EFFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7521461-B2 | Benzoic acid derivatives as modulators of PPAR alpha and gamma | ASTRAZENECA AB (SE) | 2009-04-21 | — | — | US | disclosed |