Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 4/20 | 0.64 |
| ▸ | RAB9A | P51151 | 4/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | ACHE | P22303 | 2/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.54 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.54 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.54 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.54 |
| ▸ | BCHE | P06276 | 1/20 | 0.53 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.53 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31329298 | 0.92 | ALOX5 (0.68) | KMT2AMAPK1TDP1NPC1RAB9A | |
| SCHEMBL4064581 | 0.88 | KMT2A (1.00) | KMT2ANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8790580 | 0.87 | ALDH1A1 (0.61) | KMT2AMAPK1TDP1NPC1RAB9A | |
| SCHEMBL13869716 | 0.84 | KMT2A (0.84) | KMT2ANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL417651 | 0.83 | MAPK1 (0.73) | KMT2AMAPK1TDP1NPC1RAB9A | |
| SCHEMBL8790714 | 0.83 | ALDH1A1 (0.56) | KMT2AMAPK1TDP1RAB9ASMN1; SMN2 | |
| SCHEMBL15892683 | 0.82 | KMT2A (0.67) | KMT2ANPC1RAB9AALDH1A1ACHE | |
| SCHEMBL19002580 | 0.82 | ALDH1A1 (0.69) | KMT2AMAPK1TDP1NPC1RAB9A | |
| SCHEMBL31169773 | 0.82 | RNF4 (0.68) | KMT2AMAPK1NPC1RAB9AALDH1A1 | |
| SCHEMBL18180430 | 0.81 | NPC1 (0.61) | KMT2AMAPK1NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828721-A1 | 2-AMINO-BENZOXAZINONES FOR THE TREATMENT OF VIRAL INFECTIONS | G.D. SEARLE & CO. (US) | 1998-03-18 | — | — | EP | disclosed |
| WO-1996037485-A1 | 2-AMINO-BENZOXAZINONES FOR THE TREATMENT OF VIRAL INFECTIONS | G.D. SEARLE & CO. (US) | 1996-11-28 | — | — | WO | disclosed |