Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 7/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.49 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3996108 | 0.95 | FFAR1 (0.53) | FFAR1RAB9ALMNASMN1; SMN2KDM4E | |
| SCHEMBL3996241 | 0.94 | SLC6A5 (0.50) | FFAR1MAPTRAB9APPARGTSHR | |
| SCHEMBL3998062 | 0.89 | FFAR1 (0.52) | FFAR1RAB9ALMNASMN1; SMN2KDM4E | |
| SCHEMBL3997793 | 0.89 | LTA4H (0.56) | FFAR1MAPTTSHRHSD17B10LMNA | |
| SCHEMBL3997390 | 0.89 | PPARG (0.43) | FFAR1MAPTPPARGTSHRHSD17B10 | |
| SCHEMBL3995121 | 0.88 | SLC6A5 (0.48) | FFAR1MAPTRAB9APPARGTSHR | |
| SCHEMBL13869729 | 0.87 | LMNA (0.45) | FFAR1MAPTTSHRHSD17B10LMNA | |
| SCHEMBL31123658 | 0.87 | ALDH1A1 (0.60) | MAPTRAB9ATSHRHSD17B10LMNA | |
| SCHEMBL9843420 | 0.86 | FFAR1 (0.64) | FFAR1FFAR4 | |
| SCHEMBL3997587 | 0.86 | FFAR1 (0.50) | FFAR1MAPTTSHRHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7521461-B2 | Benzoic acid derivatives as modulators of PPAR alpha and gamma | ASTRAZENECA AB (SE) | 2009-04-21 | — | — | US | disclosed |