Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 9/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 7/20 | 0.50 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.49 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9843420 | 0.85 | FFAR1 (0.64) | FFAR1FFAR4AKR1B1 | |
| SCHEMBL5989500 | 0.84 | NPC1 (0.56) | FFAR4POLBMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL3997587 | 0.83 | FFAR1 (0.50) | FFAR1FFAR4POLBMAPTSMN1; SMN2 | |
| SCHEMBL8588987 | 0.82 | MAOB (0.57) | FFAR1FFAR4POLBMAPTSMN1; SMN2 | |
| SCHEMBL4417759 | 0.81 | ALDH1A1 (0.48) | MAPTSMN1; SMN2ALDH1A1LMNAKDM4E | |
| SCHEMBL4415159 | 0.81 | TSHR (0.50) | FFAR1FFAR4SMN1; SMN2ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL4002659 | 0.81 | MAOB (0.59) | FFAR1FFAR4POLBMAPTSMN1; SMN2 | |
| SCHEMBL3997793 | 0.81 | LTA4H (0.56) | FFAR1FFAR4CYP4F2CYP4A11POLB | |
| SCHEMBL2801838 | 0.80 | ALDH1A1 (0.52) | CYP4F2CYP4A11POLBMAPTSMN1; SMN2 | |
| SCHEMBL13869719 | 0.80 | KMT2A (0.57) | FFAR1FFAR4SMN1; SMN2KDM4EAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0419844-B1 | N-hydroxy-dibenz[b,e]oxepin-alkylamines and -alkanoic acid amides, related heterocyclic analogues, a process for their preparation and their use in the manufacture of medicaments | HOECHST ROUSSEL PHARMA (US) | 1995-04-05 | — | — | EP | disclosed |
| EP-0419844-A1 | N-hydroxy-dibenz[b,e]oxepin-alkylamines and -alkanoic acid amides, related heterocyclic analogues, a process for their preparation and their use in the manufacture of medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-04-03 | — | — | EP | disclosed |