Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 10/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3986612 | 0.88 | MAPT (0.52) | MAPTLMNAALOX12ALOX5SMN1; SMN2 | |
| SCHEMBL3988992 | 0.88 | MAPT (0.67) | MAPTLMNAALOX12ALOX5SMN1; SMN2 | |
| SCHEMBL13869904 | 0.76 | SMN1; SMN2 (0.51) | MAPTLMNAALOX12ALOX5SMN1; SMN2 | |
| SCHEMBL13886692 | 0.71 | MAPT (0.60) | MAPTLMNAALOX12SMN1; SMN2ALDH1A1 | |
| SCHEMBL13343534 | 0.71 | MAPT (0.64) | MAPTLMNASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL18357522 | 0.69 | ALDH1A1 (0.53) | MAPTLMNAALOX12ALOX5SMN1; SMN2 | |
| SCHEMBL13869870 | 0.69 | MAPT (0.51) | MAPTLMNAALOX12SMN1; SMN2ALDH1A1 | |
| SCHEMBL3982203 | 0.69 | MAPT (0.64) | MAPTLMNAALOX12SMN1; SMN2ALDH1A1 | |
| SCHEMBL31351335 | 0.68 | GABRA1 (0.55) | MAPTLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL26661125 | 0.68 | GABRA1 (0.55) | MAPTLMNAALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524853-B2 | Compounds and their use in therapy | SOLVAY PHARMACEUTICALS B.V. (NL) | 2009-04-28 | — | — | US | disclosed |