Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13869988 | 0.88 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL13870025 | 0.86 | MAPT (0.33) | ALDH1A1 | |
| SCHEMBL13870022 | 0.85 | CACNA1H (0.30) | — | |
| SCHEMBL4019907 | 0.85 | ALDH1A1 (0.31) | ALDH1A1KMT2A | |
| SCHEMBL13870026 | 0.84 | — | — | |
| SCHEMBL13886801 | 0.73 | — | — | |
| SCHEMBL13869998 | 0.73 | MAT2A (0.31) | — | |
| SCHEMBL13870020 | 0.73 | MAT2A (0.31) | — | |
| SCHEMBL13886766 | 0.72 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL13869999 | 0.72 | POLB (0.38) | LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524849-B2 | Antitumor agents to treat multiple drug resistant tumors; promoters of microtubule polymerization; etherification | WYETH HOLDINGS CORPORATION (US) | 2009-04-28 | — | — | US | disclosed |