Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 4/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | RPA1 | P27694 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13870585 | 0.89 | CYP2C9 (0.49) | CYP2C9CYP2C19CYP1A2ALDH1A1CYP3A4 | |
| SCHEMBL13870588 | 0.82 | ALDH1A1 (0.66) | CYP2C9CYP2C19ALDH1A1CYP3A4CA1 | |
| SCHEMBL2915869 | 0.77 | CYP2C9 (0.63) | CYP2C9CYP2C19CYP1A2ALDH1A1CYP3A4 | |
| SCHEMBL13870589 | 0.77 | CYP1A2 (0.55) | CYP2C9CYP2C19CYP1A2ALDH1A1CA1 | |
| SCHEMBL2918680 | 0.77 | CYP2C9 (0.55) | CYP2C9CYP2C19CYP1A2ALDH1A1CYP3A4 | |
| SCHEMBL10357411 | 0.75 | CYP2C9 (0.64) | CYP2C9CYP2C19CYP1A2ALDH1A1CYP3A4 | |
| SCHEMBL3822877 | 0.73 | KDM4E (0.59) | CYP2C9CYP2C19CYP1A2ALDH1A1CYP3A4 | |
| SCHEMBL6123601 | 0.73 | CYP2C9 (0.51) | CYP2C9CYP2C19CYP1A2ALDH1A1CYP3A4 | |
| SCHEMBL6123547 | 0.73 | ALDH1A1 (0.56) | CYP2C9CYP2C19CYP1A2ALDH1A1CYP3A4 | |
| SCHEMBL4487634 | 0.70 | KDM4E (0.72) | CYP2C9CYP2C19CYP1A2ALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7521471-B2 | 4-cyanopyrazole-3-carboxamide derivatives, preparation and application thereof | SANOFI-AVENTIS (FR) | 2009-04-21 | — | — | US | disclosed |
| US-20070293541-A1 | 4-CYANOPYRAZOLE-3-CARBOXAMIDE DERIVATIVES, PREPARATION AND APPLICATION THEREOF | SANOFI-AVENTIS (FR) | 2007-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070293541-A1 | 4-CYANOPYRAZOLE-3-CARBOXAMIDE DERIVATIVES, PREPARATION AND APPLICATION THEREOF | CBR3, CNR1, CNR2 | CYP2C9 177/4885CYP2C19 248/4885CYP1A2 321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.