Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 19/20 | 0.67 |
| ▸ | MTNR1B | P49286 | 14/20 | 0.67 |
| ▸ | NQO2 | P16083 | 4/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1387144 | 0.94 | MTNR1A (0.58) | MTNR1AMTNR1BNQO2HTR2CHTR2B | |
| SCHEMBL1387212 | 0.81 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2HTR2CHTR2B | |
| SCHEMBL1387164 | 0.77 | MTNR1A (0.67) | MTNR1AMTNR1BNQO2HTR2CHTR2B | |
| SCHEMBL1387184 | 0.74 | MTNR1A (0.65) | MTNR1AMTNR1BNQO2HTR2CHTR2B | |
| SCHEMBL1387225 | 0.73 | MTNR1A (0.87) | MTNR1AMTNR1B | |
| SCHEMBL1979576 | 0.72 | HTR2B (0.50) | MTNR1AMTNR1BNQO2HTR2B | |
| SCHEMBL8284762 | 0.70 | MTNR1A (0.69) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL6945053 | 0.69 | MTNR1A (0.54) | MTNR1AMTNR1B | |
| SCHEMBL1010497 | 0.68 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL8168477 | 0.67 | MTNR1A (0.54) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-H10502336-A | — | — | 1998-03-03 | — | — | JP | claimed |
| EP-0821681-A1 | NAPHTHALENE DERIVATIVES, METHOD OF PREPARATION AND USE | GLAXO GROUP LIMITED (GB) | 1998-02-04 | — | — | EP | claimed |
| WO-1995029173-A1 | NAPHTHALENE DERIVATIVES, METHOD OF PREPARATION AND USE | GLAXO GROUP LIMITED (GB) | 1995-11-02 | — | — | WO | claimed |