SCHEMBL1387225

SCHEMBL1387225

CC(=O)NCCc1cccc2ccc3c(c12)CCO3

nearest known ligand 0.87

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 18/20 0.87
MTNR1B P49286 14/20 0.87

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1387212 0.93 MTNR1A (1.00) MTNR1AMTNR1B
SCHEMBL1387144 0.80 MTNR1A (0.58) MTNR1AMTNR1B
SCHEMBL6948606 0.78 MTNR1A (0.70) MTNR1AMTNR1B
SCHEMBL1387161 0.77 MTNR1A (1.00) MTNR1AMTNR1B
SCHEMBL1387189 0.73 MTNR1A (0.67) MTNR1AMTNR1B
SCHEMBL1010497 0.73 MTNR1A (1.00) MTNR1AMTNR1B
SCHEMBL7797256 0.72 MTNR1A (1.00) MTNR1AMTNR1B
SCHEMBL8284762 0.72 MTNR1A (0.69) MTNR1AMTNR1B
SCHEMBL4688022 0.71 MTNR1A (0.65) MTNR1AMTNR1B
SCHEMBL8168593 0.71 MTNR1A (0.65) MTNR1AMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-H10502336-A 1998-03-03 JP claimed
EP-0821681-A1 NAPHTHALENE DERIVATIVES, METHOD OF PREPARATION AND USE GLAXO GROUP LIMITED (GB) 1998-02-04 EP claimed
WO-1995029173-A1 NAPHTHALENE DERIVATIVES, METHOD OF PREPARATION AND USE GLAXO GROUP LIMITED (GB) 1995-11-02 WO claimed
EP-0821681-A1 NAPHTHALENE DERIVATIVES, METHOD OF PREPARATION AND USE GLAXO GROUP LIMITED (GB) 1998-02-04 EP disclosed
WO-1995029173-A1 NAPHTHALENE DERIVATIVES, METHOD OF PREPARATION AND USE GLAXO GROUP LIMITED (GB) 1995-11-02 WO disclosed