Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13871912 | 0.92 | PRKCI (0.35) | OXER1MCHR1SKP2DRD2HTR2A | |
| SCHEMBL13871896 | 0.89 | HTR7 (0.37) | L3MBTL1CYP2A6 | |
| SCHEMBL13872219 | 0.88 | OXER1 (0.36) | OXER1MCHR1 | |
| SCHEMBL13871860 | 0.85 | PRKCI (0.36) | MCHR1DRD3CYP2A6 | |
| SCHEMBL14818581 | 0.83 | PTK2 (0.33) | MCHR1DRD2HTR6L3MBTL1CYP2A6 | |
| SCHEMBL13872127 | 0.82 | HTR7 (0.43) | — | |
| SCHEMBL13872167 | 0.81 | KDM2B (0.32) | — | |
| SCHEMBL13872271 | 0.81 | PRKCI (0.43) | DRD2HTR2AL3MBTL1CYP2A6 | |
| SCHEMBL13872211 | 0.81 | CYP2A6 (0.35) | CYP2A6 | |
| SCHEMBL13113717 | 0.81 | MCHR1 (0.37) | MCHR1HTR2AHTR2CCYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009042907-A1 | ISOINDOLINE COMPOUNDS FOR THE TREATMENT OF SPINAL MUSCULAR ATROPHY AND OTHER USES | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2009-04-02 | — | — | WO | disclosed |