Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 16/20 | 1.00 |
| ▸ | MTNR1B | P49286 | 10/20 | 0.66 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | NQO2 | P16083 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8162658 | 0.89 | MTNR1A (0.80) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL8169118 | 0.89 | MTNR1A (0.80) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL8173300 | 0.88 | MTNR1A (0.78) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL8170080 | 0.88 | MTNR1A (0.78) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL8169375 | 0.87 | MTNR1A (0.77) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL8175008 | 0.87 | MTNR1A (0.77) | MTNR1AMTNR1BHTR2CNQO2 | |
| SCHEMBL8175004 | 0.86 | MTNR1A (0.76) | MTNR1AMTNR1BHTR2CNQO2 | |
| SCHEMBL8169388 | 0.86 | MTNR1A (0.76) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL8401104 | 0.86 | MTNR1A (0.76) | MTNR1AMTNR1BHTR2CNQO2 | |
| SCHEMBL8169871 | 0.86 | MTNR1A (0.75) | MTNR1AMTNR1BNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5998461-A | SLEEP DISORDERS | ADIR ET COMPAGNIE (FR) | 1999-12-07 | — | — | US | claimed |
| CN-1283455-A | Application of black fading hormone and black fading ligand in medicinal compsns for prevention and treatment of gastrointestional tract disease | ADIR (FR) | 2001-02-14 | — | — | CN | disclosed |
| EP-1064941-A1 | Use of melatoninergic ligands for obtaining pharmaceutical compositions for the prevention or the treatment of gastrointestinal pathologies | ADIR ET COMPAGNIE (FR) | 2001-01-03 | — | — | EP | disclosed |
| US-6071946-A | FOR TREATING DISORDERS OF THE MELATONINERGIC SYSTEM, SLEEP DISORDERS, CIRCADIAN RHYTHM DISORDERS | ADIR ET COMPAGNIE (FR) | 2000-06-06 | — | — | US | disclosed |
| US-5998461-A | SLEEP DISORDERS | ADIR ET COMPAGNIE (FR) | 1999-12-07 | — | — | US | disclosed |