Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 7/20 | 0.43 |
| ▸ | F10 | P00742 | 4/20 | 0.42 |
| ▸ | PLG | P00747 | 2/20 | 0.42 |
| ▸ | PLAU | P00749 | 2/20 | 0.42 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7395471 | 0.94 | F2 (0.43) | F2F10PLGPLAUST14 | |
| SCHEMBL7402857 | 0.93 | F10 (0.43) | F2F10PLGPLAUST14 | |
| SCHEMBL7397980 | 0.92 | F2 (0.50) | F2F10PLGPLAUST14 | |
| SCHEMBL7402180 | 0.89 | TSHR (0.36) | F10 | |
| SCHEMBL7403615 | 0.89 | PLAU (0.40) | PLAUITGB3ITGA2B | |
| SCHEMBL7398649 | 0.88 | ITGB3 (0.43) | F2F10PLGPLAUST14 | |
| SCHEMBL8488658 | 0.86 | PLAT (0.50) | F2F10PLGPLAUST14 | |
| SCHEMBL7408339 | 0.85 | PLAT (0.42) | F10PLAU | |
| SCHEMBL1387239 | 0.85 | F2 (0.45) | F2F10PLGPLAUST14 | |
| SCHEMBL7405621 | 0.84 | AKT1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-H10506122-A | — | — | 1998-06-16 | — | — | JP | claimed |
| EP-0783500-A1 | AMINOHETEROCYCLIC DERIVATIVES AS ANTITHROMBOTIC OR ANTICOAGULANT AGENTS | ZENECA LIMITED (GB) | 1997-07-16 | — | — | EP | claimed |
| WO-1996010022-A1 | AMINOHETEROCYCLIC DERIVATIVES AS ANTITHROMBOTIC OR ANTICOAGULANT AGENTS | ZENECA LIMITED (GB) | 1996-04-04 | — | — | WO | claimed |
| EP-0783500-A1 | AMINOHETEROCYCLIC DERIVATIVES AS ANTITHROMBOTIC OR ANTICOAGULANT AGENTS | ZENECA LIMITED (GB) | 1997-07-16 | — | — | EP | disclosed |
| WO-1996010022-A1 | AMINOHETEROCYCLIC DERIVATIVES AS ANTITHROMBOTIC OR ANTICOAGULANT AGENTS | ZENECA LIMITED (GB) | 1996-04-04 | — | — | WO | disclosed |