Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 6/20 | 0.45 |
| ▸ | F10 | P00742 | 5/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | PLG | P00747 | 3/20 | 0.40 |
| ▸ | PLAU | P00749 | 2/20 | 0.40 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7402863 | 0.93 | F10 (0.42) | F2F10PKMCTSSPLG | |
| SCHEMBL7403982 | 0.93 | F2 (0.42) | F2F10PKMCTSSPLG | |
| SCHEMBL7402184 | 0.89 | TSHR (0.35) | F2F10ALDH1A1 | |
| SCHEMBL7403619 | 0.89 | L3MBTL1 (0.38) | PLAUALDH1A1ITGB3ITGA2B | |
| SCHEMBL7408350 | 0.85 | CTSS (0.43) | F2F10PKMCTSSPLAU | |
| SCHEMBL1387237 | 0.85 | F2 (0.43) | F2F10PLGPLAUST14 | |
| SCHEMBL7395471 | 0.82 | F2 (0.43) | F2F10PLGPLAUST14 | |
| SCHEMBL7397980 | 0.81 | F2 (0.50) | F2F10PLGPLAUST14 | |
| SCHEMBL7404942 | 0.79 | F2 (0.43) | F2F10PKMCTSSALDH1A1 | |
| SCHEMBL7405275 | 0.79 | F10 (0.41) | F10HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-H10506122-A | — | — | 1998-06-16 | — | — | JP | claimed |
| EP-0783500-A1 | AMINOHETEROCYCLIC DERIVATIVES AS ANTITHROMBOTIC OR ANTICOAGULANT AGENTS | ZENECA LIMITED (GB) | 1997-07-16 | — | — | EP | claimed |
| WO-1996010022-A1 | AMINOHETEROCYCLIC DERIVATIVES AS ANTITHROMBOTIC OR ANTICOAGULANT AGENTS | ZENECA LIMITED (GB) | 1996-04-04 | — | — | WO | claimed |
| EP-0783500-A1 | AMINOHETEROCYCLIC DERIVATIVES AS ANTITHROMBOTIC OR ANTICOAGULANT AGENTS | ZENECA LIMITED (GB) | 1997-07-16 | — | — | EP | disclosed |
| WO-1996010022-A1 | AMINOHETEROCYCLIC DERIVATIVES AS ANTITHROMBOTIC OR ANTICOAGULANT AGENTS | ZENECA LIMITED (GB) | 1996-04-04 | — | — | WO | disclosed |