Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.56 |
| ▸ | HTR1A | P08908 | 8/20 | 0.52 |
| ▸ | HTR7 | P34969 | 8/20 | 0.52 |
| ▸ | WNT3 | P56703 | 1/20 | 0.50 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.50 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | HTR6 | P50406 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | RORC | P51449 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13873142 | 0.93 | EPHX2 (0.55) | EPHX2HTR1AHTR7WNT3SFRP1 | |
| SCHEMBL13890207 | 0.86 | EPHX2 (0.59) | EPHX2HTR1AHTR7UCHL1MEN1 | |
| SCHEMBL6538880 | 0.83 | MEN1 (0.66) | EPHX2HTR1AHTR7UCHL1MEN1 | |
| SCHEMBL13873146 | 0.83 | EPHX2 (0.56) | EPHX2HTR1AHTR7UCHL1MEN1 | |
| SCHEMBL4602370 | 0.82 | MMP13 (0.63) | HTR1AHTR7SFRP1 | |
| SCHEMBL14413047 | 0.81 | EPHX2 (0.55) | EPHX2HTR1AHTR7UCHL1MEN1 | |
| Hydrochloric Acid SCHEMBL4881432 | 0.79 | DPP4 (0.49) | EPHX2HTR1AHTR7RORC | |
| Hydrochloric Acid SCHEMBL4881423 | 0.79 | DPP4 (0.49) | EPHX2HTR1AHTR7RORC | |
| SCHEMBL13873193 | 0.78 | ALDH1A1 (0.55) | WNT3SFRP1KMT2ALMNA | |
| SCHEMBL14413609 | 0.76 | UCHL1 (0.56) | EPHX2HTR1AHTR7UCHL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090111791-A1 | Soluble Epoxide Hydrolase Inhibitors and Methods of Using Same | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-30 | — | — | US | disclosed |
| US-20090111791-A1 | Soluble Epoxide Hydrolase Inhibitors and Methods of Using Same | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090111791-A1 | Soluble Epoxide Hydrolase Inhibitors and Methods of Using Same | EPHX1, EPHX2, NCEH1 | EPHX2 2/4885HTR1A 4105/4885HTR7 2354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.