Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28673917 | 0.86 | LMNA (0.46) | LMNAALDH1A1HSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL6975034 | 0.84 | ALDH1A1 (0.45) | ALDH1A1HSD17B10TSHRSMN1; SMN2NPC1 | |
| SCHEMBL28243553 | 0.82 | ALDH1A1 (0.44) | LMNAALDH1A1HSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL21596736 | 0.81 | LMNA (0.51) | LMNAALDH1A1TSHRSMN1; SMN2KDM4E | |
| SCHEMBL28561113 | 0.81 | TYR (0.59) | LMNASMN1; SMN2TDP1CYP1A2CYP2D6 | |
| SCHEMBL446689 | 0.81 | SMN1; SMN2 (0.43) | LMNAALDH1A1HSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL2548713 | 0.80 | TAAR1 (0.50) | LMNAALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL15087374 | 0.80 | TAAR1 (0.52) | LMNAALDH1A1TYRSIRT2 | |
| SCHEMBL1821613 | 0.80 | TAAR1 (0.50) | LMNASMN1; SMN2NPC1RAB9AHIF1A | |
| SCHEMBL16244375 | 0.80 | LMNA (0.50) | LMNAALDH1A1SMN1; SMN2HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117946108-B | Nitrogen-oxygen-containing condensed ring compound, and preparation method and application thereof | 天合光能股份有限公司 | 2024-06-28 | — | — | CN | disclosed |
| CN-117946108-A | Nitrogen-oxygen-containing condensed ring compound, and preparation method and application thereof | 天合光能股份有限公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-108617166-A | Protein Kinase Inhibitor Benzolactam Compounds | 大冢制药株式会社 | 2018-10-02 | — | — | CN | disclosed |
| US-20090098541-A1 | Devices and processes for analysing individual cells | OXFORD GENE TECHNOLOGY IP LIMITED (GB) | 2009-04-16 | — | — | US | disclosed |