Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.45 |
| ▸ | FLT3 | P36888 | 11/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.42 |
| ▸ | MTOR | P42345 | 2/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.36 |
| ▸ | FYN | P06241 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13874265 | 0.82 | SRC (0.46) | MAP3K14FLT3PIK3CAMTORMKNK1 | |
| SCHEMBL3847902 | 0.80 | SLC2A1 (0.47) | MAP3K14FLT3PIK3CAMTORMKNK1 | |
| SCHEMBL3845076 | 0.77 | FLT3 (0.44) | MAP3K14FLT3PIK3CAMTORMKNK1 | |
| SCHEMBL3846450 | 0.75 | FLT3 (0.50) | MAP3K14FLT3PIK3CAMTORMKNK1 | |
| SCHEMBL13873996 | 0.75 | FLT3 (0.43) | MAP3K14FLT3PIK3CAMTORMKNK1 | |
| SCHEMBL3848841 | 0.75 | PIK3CA (0.43) | MAP3K14FLT3PIK3CAMTORMKNK1 | |
| SCHEMBL3871609 | 0.74 | SMYD3 (0.39) | MAP3K14MKNK1MKNK2 | |
| SCHEMBL3868735 | 0.73 | LMNA (0.40) | MAP3K14PIK3CAMKNK1MKNK2 | |
| SCHEMBL15756965 | 0.69 | MAP3K14 (0.54) | MAP3K14FLT3PIK3CAMTORMKNK1 | |
| SCHEMBL3849727 | 0.69 | PIK3CA (0.53) | MAP3K14FLT3PIK3CAMTORFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2048142-A2 | Nitrogen-containing condensed cyclic compound having a pyrazolyl group as a substituent group and pharmaceutical composition thereof | Eisai R&D Management Co., Ltd. (JP) | 2009-04-15 | — | — | EP | disclosed |