Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.65 |
| ▸ | MAOB | P27338 | 1/20 | 0.63 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.62 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.62 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.59 |
| ▸ | PTPRC | P08575 | 2/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.58 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.58 |
| ▸ | EGFR | P00533 | 2/20 | 0.58 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.56 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27883993 | 0.89 | ALDH1A1 (0.69) | ALDH1A1NR1H4MAOBNR4A1NR4A2 | |
| SCHEMBL5324833 | 0.86 | MAOB (0.64) | ALDH1A1NR1H4MAOBNR4A1NR4A2 | |
| SCHEMBL5324830 | 0.86 | MAOB (0.64) | ALDH1A1NR1H4MAOBNR4A1NR4A2 | |
| SCHEMBL340618 | 0.85 | MAOB (0.67) | ALDH1A1NR1H4MAOBNR4A1NR4A2 | |
| SCHEMBL9043616 | 0.85 | MAOB (0.67) | ALDH1A1MAOBNR4A1NR4A2NR4A3 | |
| SCHEMBL17978704 | 0.85 | MAOB (0.66) | ALDH1A1NR1H4MAOBNR4A1NR4A2 | |
| SCHEMBL70341 | 0.83 | ALDH1A1 (0.63) | ALDH1A1NR1H4MAOBNR4A1NR4A2 | |
| SCHEMBL5991747 | 0.83 | MAOB (0.61) | ALDH1A1NR1H4MAOBNR4A1NR4A2 | |
| SCHEMBL5991752 | 0.83 | MAOB (0.61) | ALDH1A1NR1H4MAOBNR4A1NR4A2 | |
| SCHEMBL11430643 | 0.82 | PARP10 (0.59) | ALDH1A1MAOBL3MBTL1LMNAPARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018118838-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2018-06-28 | — | — | WO | disclosed |
| US-8414982-B2 | Process for the production of strongly adherent coatings | BASF SE (DE) | 2013-04-09 | — | — | US | disclosed |
| US-20090092768-A1 | Process for the Production of Strongly Adherent Coatings | CIBA SPECIALTY CHEMICALS CORP. | 2009-04-09 | — | — | US | disclosed |