Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | PPARG | P37231 | 10/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ESRRA | P11474 | 1/20 | 0.32 |
| ▸ | MPC2 | O95563 | 1/20 | 0.32 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13875705 | 0.90 | CA2 (0.48) | CA2PPARGFFAR1THRATHRB | |
| SCHEMBL13866970 | 0.89 | CA2 (0.46) | CA2PPARGEPHX2FFAR1THRA | |
| Hydrochloric Acid SCHEMBL3873591 | 0.89 | CA2 (0.45) | CA2PPARGEPHX2FFAR1THRA | |
| SCHEMBL13875706 | 0.88 | CA2 (0.48) | CA2PPARGFFAR1THRATHRB | |
| SCHEMBL13875744 | 0.82 | MCL1 (0.42) | PPARGEPHX2ESRRAPPARA | |
| SCHEMBL13876150 | 0.81 | CA2 (0.43) | CA2PPARGFFAR1THRATHRB | |
| SCHEMBL2568386 | 0.81 | CA2 (0.45) | CA2PPARGEPHX2FFAR1THRA | |
| SCHEMBL17365879 | 0.80 | CA2 (0.47) | CA2PPARGFFAR1THRATHRB | |
| SCHEMBL13875978 | 0.80 | CA2 (0.48) | CA2PPARGFFAR1MPC2CYP2C8 | |
| SCHEMBL13876145 | 0.80 | CA2 (0.43) | CA2PPARGFFAR1MPC2CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1848700-B1 | SALTS OF (S)-2-AMINO-3-{4-[4-(2,4-DIOXO-THIAZOLIDIN-5-YLMETHYL)-PHENOXY]-PHENYL}-PROPIONIC ACID AND ITS METHYL ESTER AS INTERLEUKIN INHIBITORS FOR THE TREATMENT OF OBESITY OR DIABETES | BEXEL PHARMACEUTICALS INC (US) | 2015-12-30 | — | — | EP | disclosed |
| US-7521465-B2 | Diphenyl ether derivatives | BEXEL PHARMACEUTICALS, INC. (US) | 2009-04-21 | — | — | US | disclosed |