Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | PPARG | P37231 | 8/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MPC2 | O95563 | 1/20 | 0.35 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13875580 | 0.92 | PTPN1 (0.46) | CA2PPARGPTPN1FFAR1ALDH1A1 | |
| SCHEMBL13875978 | 0.91 | CA2 (0.48) | CA2PPARGPTPN1FFAR1ALDH1A1 | |
| SCHEMBL13876145 | 0.91 | CA2 (0.43) | CA2PPARGPTPN1FFAR1ALDH1A1 | |
| SCHEMBL13866967 | 0.89 | CA2 (0.44) | CA2PPARGPTPN1FFAR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3869871 | 0.88 | CA2 (0.43) | CA2PPARGPTPN1FFAR1ALDH1A1 | |
| SCHEMBL13875705 | 0.86 | CA2 (0.48) | CA2PPARGFFAR1MPC2CYP2C8 | |
| SCHEMBL13875697 | 0.83 | ALDH1A1 (0.51) | CA2PPARGPTPN1FFAR1ALDH1A1 | |
| SCHEMBL13875929 | 0.83 | PTPN1 (0.55) | CA2PPARGPTPN1FFAR1ALDH1A1 | |
| SCHEMBL13875706 | 0.82 | CA2 (0.48) | CA2PPARGFFAR1ALDH1A1NPSR1 | |
| SCHEMBL13875583 | 0.81 | CA2 (0.45) | CA2PPARGFFAR1MPC2CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1848700-B1 | SALTS OF (S)-2-AMINO-3-{4-[4-(2,4-DIOXO-THIAZOLIDIN-5-YLMETHYL)-PHENOXY]-PHENYL}-PROPIONIC ACID AND ITS METHYL ESTER AS INTERLEUKIN INHIBITORS FOR THE TREATMENT OF OBESITY OR DIABETES | BEXEL PHARMACEUTICALS INC (US) | 2015-12-30 | — | — | EP | disclosed |
| US-7521465-B2 | Diphenyl ether derivatives | BEXEL PHARMACEUTICALS, INC. (US) | 2009-04-21 | — | — | US | disclosed |