Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.43 |
| ▸ | DPP4 | P27487 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | DCK | P27707 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13876297 | 0.83 | DPP4 (0.45) | HTR2CDPP4CYP1A2CYP3A4HPGD | |
| SCHEMBL13876930 | 0.82 | DPP4 (0.38) | HTR2CDPP4KDM4EKMT2AHSD17B10 | |
| SCHEMBL13866856 | 0.78 | DPP4 (0.54) | HTR2CDPP4 | |
| SCHEMBL13875671 | 0.77 | DPP4 (0.38) | DPP4KDM4ECYP1A2CYP3A4MAPT | |
| SCHEMBL13876102 | 0.76 | DPP4 (0.53) | HTR2CDPP4MEN1LMNACYP1A2 | |
| SCHEMBL10244864 | 0.75 | DPP4 (0.49) | DPP4CYP3A4 | |
| SCHEMBL13875846 | 0.74 | TLR7 (0.41) | DPP4MEN1KMT2APOLBSIRT5 | |
| SCHEMBL13875849 | 0.74 | DPP4 (0.39) | HTR2CDPP4POLBSIRT5 | |
| Trifluoroacetic Acid SCHEMBL3874196 | 0.72 | DPP4 (0.48) | DPP4 | |
| SCHEMBL13875673 | 0.72 | DPP4 (0.40) | DPP4MEN1CYP1A2CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524847-B2 | Fused 1,3-dihydro-imidazole ring compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-04-28 | — | — | US | disclosed |