Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13876297 | 0.84 | DPP4 (0.45) | DPP4CYP1A2ALDH1A1TSHRHTR1A | |
| SCHEMBL13875849 | 0.83 | DPP4 (0.39) | DPP4POLBSIRT5HTR2CTLR7 | |
| SCHEMBL13876315 | 0.80 | DPP4 (0.51) | DPP4CYP1A2ALDH1A1TSHRPOLB | |
| SCHEMBL13875672 | 0.80 | MAPT (0.38) | DPP4ALDH1A1POLBSIRT5MAPK1 | |
| SCHEMBL13875671 | 0.80 | DPP4 (0.38) | DPP4CYP1A2ALDH1A1TSHRPOLB | |
| SCHEMBL13875846 | 0.77 | TLR7 (0.41) | DPP4ALDH1A1POLBSIRT5TLR7 | |
| SCHEMBL13875752 | 0.76 | HTR2C (0.43) | DPP4CYP1A2HTR1APOLBSIRT5 | |
| SCHEMBL13866853 | 0.76 | DPP4 (0.62) | DPP4 | |
| SCHEMBL13876930 | 0.75 | DPP4 (0.38) | DPP4ALDH1A1POLBSIRT5HSD17B10 | |
| SCHEMBL13875683 | 0.73 | SLC2A1 (0.53) | CYP1A2ALDH1A1TSHRCYP2C19CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524847-B2 | Fused 1,3-dihydro-imidazole ring compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-04-28 | — | — | US | disclosed |