Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.56 |
| ▸ | HTR1A | P08908 | 4/20 | 0.47 |
| ▸ | HTR7 | P34969 | 4/20 | 0.47 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.46 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 3/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR5A | P47898 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.44 |
| ▸ | HTR3B | O95264 | 2/20 | 0.44 |
| ▸ | HTR3A | P46098 | 2/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30931000 | 0.88 | HTR7 (0.51) | SLC6A2SLC6A3HTR1AHTR7PLD1 | |
| SCHEMBL30931122 | 0.74 | HTR7 (0.44) | SLC6A2SLC6A3HTR1AHTR7HTR6 | |
| SCHEMBL21523722 | 0.74 | RAB9A (0.77) | RAB9ANPC1SMN1; SMN2MEN1HPGD | |
| SCHEMBL24719517 | 0.73 | SLC6A2 (0.42) | SLC6A2SLC6A3HTR1AHTR7PLD1 | |
| SCHEMBL30123979 | 0.73 | SLC6A2 (0.42) | SLC6A2SLC6A3HTR1AHTR7PLD1 | |
| Bromide SCHEMBL29182849 | 0.72 | SLC6A2 (0.41) | SLC6A2SLC6A3PLD1RAB9ANPC1 | |
| SCHEMBL6032840 | 0.72 | CHRNA7 (0.55) | RAB9ANPC1NOTUMSMN1; SMN2HTR3A | |
| SCHEMBL28603671 | 0.72 | SLC6A2 (1.00) | SLC6A2SLC6A3HTR1ARAB9ANPC1 | |
| SCHEMBL20325708 | 0.71 | CYP1A2 (0.48) | SLC6A2SLC6A3PLD1ADRB1NCF1 | |
| SCHEMBL3442456 | 0.70 | DYRK1A (0.64) | HTR1AHTR7PLD1CSNK1DMAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771421-B1 | N-HYDROXYAMIDE DERIVATIVES AND USE THEREOF | SERONO LAB (CH) | 2009-04-29 | — | — | EP | disclosed |