Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1388072 | 0.84 | — | — | |
| SCHEMBL1387973 | 0.81 | — | — | |
| SCHEMBL1388119 | 0.81 | — | — | |
| SCHEMBL7417663 | 0.80 | — | — | |
| SCHEMBL1388312 | 0.79 | NTRK1 (0.43) | — | |
| SCHEMBL1388045 | 0.79 | — | — | |
| SCHEMBL1387932 | 0.79 | — | — | |
| SCHEMBL1387879 | 0.78 | — | — | |
| SCHEMBL1387813 | 0.77 | PDE2A (0.43) | — | |
| SCHEMBL1387500 | 0.75 | STK33 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0752992-B1 | IMIDAZO[1,2-a]INDENO[1,2-e]PYRAZIN-4-ONE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | AVENTIS PHARMA SA (FR) | 2001-05-30 | — | — | EP | claimed |
| JP-H09510727-A | — | — | 1997-10-28 | — | — | JP | claimed |
| EP-0752992-A1 | IMIDAZO(1,2-A)INDENO(1,2-E)PYRAZINE-4-ONE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Aventis Pharma S.A. (FR) | 1997-01-15 | — | — | EP | claimed |
| WO-1995026350-A1 | IMIDAZO(1,2-A)INDENO(1,2-E)PYRAZINE-4-ONE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | RHONE-POULENC RORER S.A. (FR) | 1995-10-05 | — | — | WO | claimed |
| EP-0752992-B1 | IMIDAZO[1,2-a]INDENO[1,2-e]PYRAZIN-4-ONE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | AVENTIS PHARMA SA (FR) | 2001-05-30 | — | — | EP | disclosed |
| US-5807859-A | ANTIISCHEMIC AGENTS; BRAIN DISORDERS | RHONE-POULENC RORER S.A. (FR) | 1998-09-15 | — | — | US | disclosed |
| EP-0752992-A1 | IMIDAZO(1,2-A)INDENO(1,2-E)PYRAZINE-4-ONE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Aventis Pharma S.A. (FR) | 1997-01-15 | — | — | EP | disclosed |
| WO-1995026350-A1 | IMIDAZO(1,2-A)INDENO(1,2-E)PYRAZINE-4-ONE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | RHONE-POULENC RORER S.A. (FR) | 1995-10-05 | — | — | WO | disclosed |