Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | EDNRA | P25101 | 5/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9056690 | 0.86 | KDM4E (0.44) | ALDH1A1KDM4ELMNANPC1MEN1 | |
| SCHEMBL361847 | 0.86 | KDM4E (0.50) | ALDH1A1KDM4ELMNANPC1MEN1 | |
| SCHEMBL30284405 | 0.86 | KDM4E (0.50) | ALDH1A1KDM4ELMNANPC1MEN1 | |
| SCHEMBL1387871 | 0.83 | NPC1 (0.38) | ALDH1A1KDM4ELMNANPC1MEN1 | |
| SCHEMBL2517095 | 0.82 | KDM4E (0.45) | ALDH1A1KDM4ELMNANPC1MEN1 | |
| SCHEMBL9104399 | 0.80 | KDM4E (0.40) | ALDH1A1KDM4ELMNANPC1MEN1 | |
| SCHEMBL7821439 | 0.79 | NPC1 (0.37) | ALDH1A1KDM4ELMNANPC1MEN1 | |
| SCHEMBL5615321 | 0.78 | SMN1; SMN2 (0.43) | ALDH1A1KDM4ELMNANPC1MEN1 | |
| SCHEMBL5615529 | 0.78 | ALDH1A1 (0.42) | ALDH1A1KDM4ELMNANPC1MEN1 | |
| SCHEMBL7818422 | 0.78 | ALDH1A1 (0.39) | ALDH1A1KDM4ELMNANPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1053445-C | Photochromic naphthopyran compounds | PPG INDUSTRIES INC (US) | 2000-06-14 | — | — | CN | claimed |
| JP-H08512031-A | — | — | 1996-12-17 | — | — | JP | claimed |
| CN-1125985-A | Photochromic naphthopyran compounds | PPG INDUSTRIES INC (US) | 1996-07-03 | — | — | CN | claimed |
| EP-0704067-A1 | PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS | PPG INDUSTRIES, INC. (US) | 1996-04-03 | — | — | EP | claimed |
| EP-0704067-A4 | PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS | PPG INDUSTRIES INC (US) | 1996-02-02 | — | — | EP | claimed |
| US-5384077-A | Naphthopyrans | TRANSITIONS OPTICAL, INC. (US) | 1995-01-24 | — | — | US | claimed |
| WO-1995000866-A1 | PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS | PPG INDUSTRIES, INC. (US) | 1995-01-05 | — | — | WO | claimed |
| EP-0704067-B1 | PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS | PPG IND OHIO INC (US) | 2001-08-01 | — | — | EP | disclosed |
| CN-1053445-C | Photochromic naphthopyran compounds | PPG INDUSTRIES INC (US) | 2000-06-14 | — | — | CN | disclosed |
| CN-1125985-A | Photochromic naphthopyran compounds | PPG INDUSTRIES INC (US) | 1996-07-03 | — | — | CN | disclosed |
| EP-0704067-A1 | PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS | PPG INDUSTRIES, INC. (US) | 1996-04-03 | — | — | EP | disclosed |
| EP-0704067-A4 | PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS | PPG INDUSTRIES INC (US) | 1996-02-02 | — | — | EP | disclosed |
| US-5458815-A | Photochromic naphthopyran compounds | TRANSITIONS OPTICAL, INC. (US) | 1995-10-17 | — | — | US | disclosed |
| US-5384077-A | Naphthopyrans | TRANSITIONS OPTICAL, INC. (US) | 1995-01-24 | — | — | US | disclosed |
| WO-1995000866-A1 | PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS | PPG INDUSTRIES, INC. (US) | 1995-01-05 | — | — | WO | disclosed |