Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | GLA | P06280 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | HNF4A | P41235 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9056690 | 0.85 | KDM4E (0.44) | KDM4EALDH1A1HPGDMAPTGLA | |
| SCHEMBL30284405 | 0.85 | KDM4E (0.50) | KDM4EALDH1A1HPGDMAPTGLA | |
| SCHEMBL361847 | 0.85 | KDM4E (0.50) | KDM4EALDH1A1HPGDMAPTGLA | |
| SCHEMBL2517095 | 0.81 | KDM4E (0.45) | KDM4EALDH1A1HPGDMAPTGLA | |
| SCHEMBL9257841 | 0.81 | KDM4E (0.41) | KDM4EALDH1A1HPGDMAPTGLA | |
| SCHEMBL1387642 | 0.80 | ALDH1A1 (0.40) | KDM4EALDH1A1HPGDMAPTGLA | |
| SCHEMBL1387871 | 0.77 | NPC1 (0.38) | KDM4EALDH1A1HPGDMAPTGLA | |
| SCHEMBL5615529 | 0.77 | ALDH1A1 (0.42) | KDM4EALDH1A1HPGDMAPTGLA | |
| SCHEMBL5615321 | 0.77 | SMN1; SMN2 (0.43) | KDM4EALDH1A1HPGDMAPTGLA | |
| SCHEMBL5094572 | 0.77 | KDM4E (0.40) | KDM4EALDH1A1HPGDMAPTGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552091-A | PHOTOCHROMIC, LENSES | PPG INDUSTRIES, INC. (US) | 1996-09-03 | — | — | US | disclosed |