Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24508042 | 0.73 | APLNR (0.33) | — | |
| SCHEMBL9382526 | 0.69 | APLNR (0.33) | — | |
| SCHEMBL17451650 | 0.69 | HSD11B1 (0.30) | — | |
| SCHEMBL15629712 | 0.69 | HSD11B1 (0.30) | — | |
| SCHEMBL5669103 | 0.69 | — | — | |
| SCHEMBL25069360 | 0.69 | — | — | |
| SCHEMBL18160268 | 0.69 | — | — | |
| SCHEMBL15139341 | 0.67 | — | — | |
| SCHEMBL11955215 | 0.67 | RECQL (0.34) | ALDH1A1 | |
| SCHEMBL13877831 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150232439-A1 | PROCESS FOR THE PREPARATION OF C-FMS KINASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2015-08-20 | — | — | US | disclosed |
| US-9029352-B2 | Process for the preparation of C-FMS kinase inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2015-05-12 | — | — | US | disclosed |
| US-8901314-B2 | Substituted pyrazoles as N-type calcium channel blockers | JANSSEN PHARMACEUTICA NV (BE) | 2014-12-02 | — | — | US | disclosed |
| US-20140163031-A1 | SUBSTITUTED PYRAZOLES AS N-TYPE CALCIUM CHANNEL BLOCKERS | JANSSEN PHARMACEUTICA NV (BE) | 2014-06-12 | — | — | US | disclosed |
| US-20140045789-A1 | PROCESS FOR THE PREPARATION OF C-FMS KINASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2014-02-13 | — | — | US | disclosed |
| US-8497376-B2 | 4-Cyano-1H-imidazole-2-carboxylic acid [2-cyclohex-1-enyl-4-(2,6-dioxo-piperidin-4-yl)-phenyl]-amide; tyrosine kinase inhibitor; autoimmune diseases, antiinflammatory, anticarcinogenic agent | JANSSEN PHARMACEUTICA N.V. (BE) | 2013-07-30 | — | — | US | disclosed |
| US-20090105296-A1 | INHIBITORS OF C-FMS KINASE | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150232439-A1 | PROCESS FOR THE PREPARATION OF C-FMS KINASE INHIBITORS | FLT3, FES, FER | ALDH1A1 4200/4885TDP1 3955/4885 |
| US-20140163031-A1 | SUBSTITUTED PYRAZOLES AS N-TYPE CALCIUM CHANNEL BLOCKERS | CACNA1B, CACNA1E, CACNA1A | ALDH1A1 3178/4885TDP1 3675/4885 |
| US-20090105296-A1 | INHIBITORS OF C-FMS KINASE | MUSK, FRK, FES | ALDH1A1 4702/4885TDP1 2261/4885 |
| US-20140045789-A1 | PROCESS FOR THE PREPARATION OF C-FMS KINASE INHIBITORS | FLT3, FES, FER | ALDH1A1 4200/4885TDP1 3955/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.